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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

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Editor's Pick

From Emergency Use Authorization to 510(k) Clearance: Preparing Physician Offices for the December 2026 Transition

For physician offices that perform respiratory testing, December 26, 2026 is more than a date on the calendar. It is the day the federal declarations supporting emergency use authorization (EUA) of certain COVID-19 medical devices, including in vitro diagnostic tests used to detect or diagnose SARS-CoV-2, are scheduled to terminate.3 On June 29, 2026, the U.S. Department of Health and Human Services (HHS) Secretary determined that circumstances no longer exist to justify those declarations, and...

Showing 1–12 of 2,098 articles

PubMed

Correction: Addressing risk factors for hypertensive disorders in pregnancy: A case study of a quality improvement program in two states in Nigeria.

The Funding statement for this article is incorrect. The correct Funding statement is as follows: This study was financially supported by MSD for Mothers in the form of a grant awarded to and administered to the authors by Jhpiego Corporation. No additional external funding was received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The Competing Interests statement for this article is incorrect. The...

Articles
Okoli U, Obafemi S, Okpe C, Njoku K, Mobisson N, Uzoama C, Omoera V, Ugwa E, Hill K•
PubMed

Feasibility and acceptability of a structured counselling approach to address lifestyle-related risk factors during pregnancy and postpartum care: an exploratory longitudinal pilot feasibility study.

Background Lifestyle-related risk factors (LRRFs) are major contributors to adverse maternal and child outcomes. Despite clear international guidelines, counselling on these topics is inconsistently implemented in routine care. Structured tools may support comprehensive, consistent counselling, yet evidence for multi-domain approaches in maternal health is limited. Methods This exploratory longitudinal pilot feasibility study evaluated a structured counselling approach to support structured c...

Articles
Bombana M, Kraufmann K, Krug K, Wensing M•
PubMed

HIF-1α expression is associated to cell proliferation and ECM production in temporomandibular joint osteoarthritis.

Temporomandibular joint osteoarthritis (TMJOA) is a complex joint disorder characterized by progressive degradation of the cartilage matrix and apoptosis of chondrocytes; however, hypoxia-inducible factor 1α (HIF-1α) serves a positive role in maintaining the stability of the articular cartilage matrix. Therefore, the present study aimed to determine the expression levels of HIF-1α in the cartilage tissue of rats with TMJOA, and to explore its association with the proliferation of chondrocytes an...

Articles
Liu L, Shi X, Li X, Lin Y, Yang H, Zhang J, Yang C•
PubMed

Illness perceptions among adults aged 18–44 years with ankylosing spondylitis: A qualitative study informed by the common-sense model of self-regulation.

Background Ankylosing spondylitis mainly affects people in early and middle adulthood. This period involves important transitions in education, career, relationships, and family. Illness perceptions play an important role in treatment adherence and disease management. Few qualitative studies have examined how Chinese adults perceive and cope with the disease using a clear theoretical framework. Objective This study aimed to explore illness perceptions among adults aged 18–44 years with ankylo...

Articles
Zhu D, Wang B, Li Y, Nie X, Yin H, Huang S, Wang Q, Xu R•
PubMed

Laboratory-based assessment of quantitative PCR to describe Arctic fish assemblages in surface water affected by acid rock drainage.

Permafrost thaw has been identified as a cause of metal mobilization from acid rock drainage and transport to Arctic rivers. Elevated metal concentrations and precipitation of Fe(III) minerals (i.e., rusting) in surface waters deteriorates water quality and raises questions about ecosystem effects, especially to the health of fish species. Environmental DNA (eDNA) analyses could be used for assessing impacts of acid rock drainage to fish assemblages but may be prone to biases like polymerase cha...

Articles
Scott LC, Ramey AM, Riddle-Berntsen AE, Poulin BA, Koch JC, O’Donnell JA, Carey MP•
PubMed

Effectiveness of LGBTQ targeted cognitive behavioral therapy on mental health outcomes: A systematic review and meta-analysis protocol.

Introduction Sexual and gender minority populations experience disproportionately high rates of mental disorders due, in large part, to their chronic exposure to stigma, discrimination, and minority stress. Cognitive behavioral therapy (CBT) is an established evidence-based psychotherapy; however, conventional CBT was primarily developed among predominantly cisgender, heterosexual individuals and not often addresses identity-specific stressors relevant to LGBTQ individuals. Emerging adaptations...

Articles
Chi JD, Yang Y, Wang SY, Nyhan K, Jackson SD•
PubMed

Decolonizing mental health: the Nova Scotia transcultural mental health program as a model of care.

Background African Nova Scotians, Indigenous peoples, and refugees experience significant disparities in access to culturally appropriate mental health care due to systemic inequities, intergenerational trauma, stigma, and limited availability of culturally competent services. The Nova Scotia Transcultural Mental Health Program (NSTMHP) was established to close gaps in serving these equity-denied groups using a culturally responsive and collaborative model of care in primary healthcare settings...

Articles
Cassidy KL, Ursuliak Z, Holland T, MacDonell KC, Milne R, Daigle P, Johnson S, Sridharan S, Williams O, Sulyman M, Morrison J, Awara M, Natarajan A, Edem D, Agyapong B, Eboreime E, Agyapong VIO•
PubMed

Psychosocial influences on hypertension in Southeastern Nigeria: A mixed-methods study protocol.

Introduction The Southeastern region of Nigeria faces a severe public health challenge from hypertension due to its high prevalence. Psychosocial factors including perceived stress, anxiety, depression, coping mechanisms, and social support play essential roles in hypertension development and health behaviour, yet there has been limited scholarly attention to these determinants in Nigerian and international qualitative research. This study addresses this evidence gap by investigating the psycho...

Articles
Ebigwei Omeda AR, Chilaka M, Mohammadnezhad M, Vaportzis E•
PubMed

Dirozalkib versus Crizotinib in Advanced Anaplastic Lymphoma Kinase Inhibitor-Naïve ALK-Positive Non-Small-Cell Lung Cancer: A Multicenter, Randomized Phase III Trial.

Background: Dirozalkib is a highly selective anaplastic lymphoma kinase (ALK) inhibitor with intracranial antitumor activity against crizotinib-resistant mutations. This phase III trial evaluated dirozalkib versus crizotinib in patients with ALK inhibitor-naïve, ALK-positive, advanced non-small-cell lung cancer (NSCLC). Methods: In this multicenter, randomized, open-label DIAMOND-2 trial, adult patients with ALK inhibitor-naïve, ALK-positive, advanced NSCLC who either had received no prior syste...

Articles
Liu Y, Meng X, Yu Y, Chen J, Yang R, Liu L, Zhao Y, Tian R, Li D, Ning R, Li Q, Wu G, Wang L, Duan X, Guo X, Hu Y, Liu W, Liu H•
PubMed

Geometry based gene-expression signatures detect cancer treatment responders in clinical trials.

Background Topological data analysis has had many developments with potential application to precision oncology. The goal of this study is to determine if using geometry-based methods of gene-expression signatures of tumors can be used to both create a definitive classification of responders and non-responders, and to predict patient treatment response using out-of-sample testing methodology. Methods Gene-expression signatures of tumors, constructed from geometrical attributes of data, were c...

Articles
Chachólski W, Ramanujam R•
PubMed

Mobile Apps Addressing Feeding of Children With Autism: Systematic Search and Content and Quality Analysis.

Abstract Background Approximately 1 in 100 children worldwide are diagnosed with autism spectrum disorder (ASD), and 46% to 89% of those diagnosed experience significant feeding difficulties. Mobile health (mHealth) apps are a potential tool for scalable support. However, there is nascent literature on the quality and relevance of mHealth apps for managing ASD-related feeding challenges. Objective This study aimed at systematically identifying and reviewing the content, behavior change strat...

Articles
Mukarage F, Cofie Kuzagbe C, Nandi Adams S, Yves-Roland Douha N, Talina Luhanga E•