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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 157–168 of 373 articles

PLOS

Reliability and criterion validity of abductor hallucis muscle volume measurements using ultrasound and MRI by assessors with limited image analysis experience

Purpose: The abductor hallucis (ABDH) contributes to foot function and mobility, which can influence quality of life, making accurate assessment of muscle volume important. While magnetic resonance imaging (MRI) is often considered to be the reference standard of medical imaging, ultrasound (US) provides a cost-effective, rapid and dynamic way of assessing muscle size and function. This study aimed to evaluate the criterion validity and intrarater reliability of US-derived ABDH muscle volume mea...

Ultrasound
Jacob B. Willes, Emma Robinson, Joshua K. Sponbeck, Derek A. Swanson, Dallin C. Swanson, Austin G. Goodrich, Steven P. Allen, A. Wayne Johnson•
PLOS

Expression of Concern: Digital economy, innovation factor allocation and industrial structure transformation—A case study of the Yangtze River Delta city cluster in China

The PLOS One Editors issue this Expression of Concern because this article [ 1 ] was identified as one of a series of submissions for which we have concerns about the integrity and/or reliability of the peer review process. Readers are advised to interpret the article [ 1 ] with consideration of this issue. In following up on this matter, PLOS did not evaluate the article’s integrity or scientific validity. The Editors do not have concerns regarding the authors’ conduct during the peer review...

Aed
The PLOS One Editors•
PLOS

Analysis of the impact of naturally-acquired immunity on Shigella vaccine performance to inform clinical trials: A simulation-based modeling study

Background: Effective vaccines against Shigella, the leading bacterial cause of diarrheal disease globally, could prevent morbidity and mortality from shigellosis as well as limit antibiotic resistance. Several Shigella vaccine candidates are in late stages of development, and the design of large Phase 3 trials in target populations is underway. In high incidence settings, children are expected to rapidly accrue natural immunity such that after repeated pathogen exposure, unvaccinated infants ma...

Vaccines And Immunization
Avnika B. Amin, Maria Garcia Quesada, Daniel Trudell, Natalie E. Dean, Benjamin A. Lopman, James A. Platts-Mills, Elizabeth T. Rogawski McQuade•
PLOS

Vimentin neutralizing antibody ameliorate inflammatory bowel disease by inhibiting fibrosis and inflammatory cell death

Background: Inflammatory bowel disease (IBD) is characterized by chronic inflammation intertwined with fibrosis and increased necroptosis. Vimentin, an intermediate filament protein closely associated with fibrosis and several inflammatory pathways, is elevated in IBD tissues. We conducted experiments to determine the effect of neutralization of extracellular vimentin with an anti-vimentin antibody (Ab) on the pathogenesis of IBD. Methods: IBD was mimicked in a 7-week C57BL6 mice by mixing 3% de...

Inflammatory Bowel Disease
Sol Kim, Hye Yeon Kang, Jin-Sil Park, JeongWon Choi, Ha Yeon Jeong, Seon Yeong Lee, Han Hee Lee, Bo-In Lee, Mi-La Cho•
PLOS

Risk factors for syphilis among newly admitted prisoners: A case–control study

Background: Syphilis remains a major global public health concern in various groups, including people in prisons, where the burden is substantial. This study aimed to identify factors associated with syphilis infection among newly admitted prisoners in a province of Thailand. Methods: A case–control study was conducted among newly admitted prisoners in three correctional facilities. Cases and controls were randomly selected from newly admitted prisoners who had undergone syphilis screening at pr...

Syphilis
Thanaset Hiranbandit, Wutthichai Jariya•
PLOS

Fluctuations of micronutrients during pregnancy in Lianyungang, Jiangsu, China: A prospective longitudinal cohort study

Pregnancy is accompanied by substantial physiological adaptations that may alter maternal micronutrient concentrations. A prospective longitudinal pregnancy-neonatal cohort of 51 healthy pregnant women was established at 6–8 weeks of gestation in Lianyungang, Jiangsu, China, confirmed by fetal heart and bud on B-ultrasound. Pregnancy complications, outcomes, and neonatal health at day 42 were confirmed. Forty-three women who completed all assessments and had uncomplicated pregnancies with favora...

Pregnancy
Lianshuai Zheng, Xiaolun Xu, Xueyuan Rong, Jian Luo, Guoqing Chen, Cheng Zhao•
PLOS

Age-stratified prevalence and associated risk factors of hypertension, diabetes and hypercholesterolemia in Nepal: Insights from the STEPS survey 2019

Background: Non-communicable diseases (NCDs) are a major global public health challenge, particularly in low- and middle-income countries such as Nepal. Despite the growing burden of hypertension, diabetes, and hypercholesterolemia, limited evidence exists on age-stratified patterns of NCDs and associated risk factors, especially among younger populations. This study investigated age-stratified prevalence of hypertension, diabetes and hypercholesterolemia and risk factors in Nepal to inform age-...

Hypercholesterolemia
Durga Datta Chapagain, Kennedy Mensah Osei, Iga Danik Prasiska, Vasuki Rajaguru, Sunjoo Kang, Heejin Kimm, Tae Hyun Kim, Sang Gyu Lee, Whiejong Han•
PLOS

Pain experiences of Tibetan children with hematologic malignancies in China: A descriptive phenomenological study

Background: Pain is common in children with hematologic malignancies. It can be highly distressing and can shape how children feel and function during hospitalization. Children’s pain experiences are influenced not only by disease and treatment but also by developmental level, family context, language, and culture. However, little is known about how Tibetan children with hematologic malignancies experience and communicate pain in clinical settings. Aim: We aimed to explore the pain experiences o...

Hematology
Yi Chen, Yu Liu, Juan Zhou, Huarong Pu, Jinglan Zhang•
PLOS

Histopathologic spectrum of focal liver lesions diagnosed by ultrasound-guided percutaneous liver biopsy and predictors of hepatocellular carcinoma: A single-center experience from Sub-Saharan Africa

Background: Focal liver lesions (FLLs) encompass a wide spectrum of benign and malignant pathologies, and accurate diagnosis is essential for appropriate management. Although advances in imaging have improved lesion characterization, histopathologic assessment remains the diagnostic gold standard for indeterminate lesions. Data on the histopathologic spectrum and diagnostic utility of ultrasound-guided percutaneous liver biopsy (US-PLB) in sub-Saharan Africa (SSA) are limited. This study aimed t...

Ultrasound
Tamrat Petros Elias, Abate Bane Shewaye, Kaleb Assefa Berhane, Abdu Mohammed, Zebeaman Tibebu, Amanuel Getu Gebreselassie, Abraham Sisay Abie•
PLOS

Design and verification of an interlocked centrifugal exhaust system for hatch-type boiling disinfectors

Objective: To address the occupational exposure risks caused by instantaneous steam overflow when opening the top cover of hatch-type boiling disinfectors in the central sterile supply department, this study developed an interlocked centrifugal exhaust system (ICES) characterized by operational simplicity and high adaptability. Methods: The ICES was assembled using a centrifugal fan, Hall effect switch, instant relay, time-delay relay, solid-state relay, and piping. The system achieved automatic...

Centrifuge
Xiaoxue Sun, Qinqin Wang, Wei Zheng•
PLOS

Correction: Comparative study of thoracolumbar fascia changes in weightlifters with and without low back pain

The eighth and ninth authors are listed out of order. The correct order is: Emma Feng Ming Zhou 1 , Carmelo Pirri 2 , Xiaoxiao Zhao 2 , Juhua Peng 3 , Tao Wen 3 , Jianhui Fang 3 , Chufeng Zhou 3 , Carla Stecco 2 , Siu Ngor Fu 1 1 Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, 2 Department of Neurosciences, Institute of Human Anatomy, University of Padova, Padova, Italy, 3 Department of Rehabilitation, Guangdong Sports Hospital, Guangzhou, Guang...

Back Pain
Emma Feng Ming Zhou, Carmelo Pirri, Xiaoxiao Zhao, Juhua Peng, Tao Wen, Jianhui Fang, Chufeng Zhou, Carla Stecco, Siu Ngor Fu•

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