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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,873–1,884 of 1,994 articles

PubMed

A Narrative Review of Weight Management Strategies: From Lifestyle Interventions to Emerging Pharmacotherapies.

Background Obesity is a chronic, multifactorial disease associated with significant cardiometabolic, psychological, and socioeconomic consequences. Its complex etiology necessitates integrated, evidence‐based management strategies beyond simple caloric restriction. Objective This narrative review aims to critically evaluate current and emerging weight management strategies, including lifestyle interventions, dietary patterns, behavioral approaches, pharmacotherapy, and bariatric procedures, w...

Weight Management
Ahmed IS, Tapponi SL, Manaa HM, Soltani A, Hussein ES, Parvaresh FA, Hussain Z•
PubMed

From Thesis to Publication: A Five-Year Cross-Disciplinary Analysis in Pathology, Urology, and Endocrinology (2018-2022).

Objective: Despite the legal requirement to complete a thesis during residency training in Türkiye, the extent to which these theses are translated into high-quality scientific publications remains unclear. Disciplinary differences in research culture, resource availability, and clinical workload may influence these outcomes. Material and Methods: This cross-sectional study analyzed 1245 open access residency theses completed between 2018 and 2022 in the fields of pathology (n=344), endocrinolo...

Urology
Tunce EB, Bayrak BY, Akgul M•
PubMed

Comments on "Use of ChatGPT in Urology and its Relevance in Clinical Practice": To-ward a Responsible AI Framework for Middle-Income Settings.

To the editor, We read with interest the article by Braga et al. evaluating ChatGPT's accuracy and reproducibility in pediatric urology (1). The study highlights important limitations: although ChatGPT can provide partially correct answers, it also produces incomplete, ambiguous, or potentially misleading responses—particularly regarding diagnostic definitions and treatment recommendations. We also noted a minor typographical error in the abstract ("those rwere evaluated qualitatively…"), which...

Urology
Osorio JMM•
PubMed

Targeted Ultrasound With Contrast Enhancement for Reassessment of MRI-Detected BI-RADS 4 Nonmass Enhancement: Impact on Biopsy Reduction and DCIS Detection.

Objective To evaluate whether targeted ultrasound (TUS) combined with contrast‐enhanced ultrasound (CEUS) can safely reclassify MRI‐detected BI‐RADS 4 nonmass enhancement (NME) lesions to reduce unnecessary biopsies while maintaining high diagnostic sensitivity for breast cancer. Materials and Methods In this prospective study (2017–2023), we enrolled 169 MRI‐detected BI‐RADS 4 NME lesions in 167 women (23–84 years). All patients underwent TUS and CEUS within one week after MRI, followed by s...

Ultrasound
Niu Q, Sun T, Li M, Du L, Cai Y, Jin L, Jia C, Li H, Chen A, Li F•
PubMed

Ultrasound Features of Female Adnexal Tumor of Probable Wolffian Origin (FATWO): A Case Series and Literature Review.

Introduction Female adnexal tumor of probable Wolffian origin (FATWO) is an extremely rare gynecologic neoplasm derived from mesonephric duct remnants. It exhibits nonspecific clinical and imaging features, frequently leading to preoperative misdiagnosis. To date, ultrasound findings of FATWO remain poorly characterized, with limited systematic reports. This study summarizes the ultrasonic manifestations of four pathologically confirmed FATWO cases and reviews the literature, aiming to improve...

Ultrasound
Xu L, Ye L, Chu K, Wang J•
PubMed

Frailty as a Key Determinant of Cardiovascular Risk and Mortality in Preserved Ratio Impaired Spirometry: A Nationally Representative Study.

ABSTRACT Background Preserved ratio impaired spirometry (PRISm) is associated with elevated cardiovascular disease (CVD) risk and progression to COPD, but the underlying mechanisms remain unclear. Frailty is known to worsen outcomes in COPD; however, its role in PRISm has not been well defined. This study examined factors associated with cardiovascular events and mortality in PRISm and developed risk models. Methods We analyzed 8882 adults (aged 20–79 years) from NHANES 2007–2012, identifyin...

Spirometry
Ren Y, Wu Y, Hu W, Liu L, Cai H, Zhang J•
PubMed

Performance Evaluation of Nucleic Acid Detection Reagents and Verification of Various Factors Affecting the Efficiency of Nucleic.

Background: Since the COVID-19 outbreak in 2019, nucleic acid testing has been central to epidemic control and clinical decision-making. However, variability in assay kits and extraction steps can affect sensitivity, specificity, and reproducibility. Systematic evaluation of detection reagents and extraction efficiency is essential to ensure reliable clinical results. Objective: This study aimed to evaluate whether three domestic novel coronavirus nucleic acid detection kits based on fluoresc...

Reagents
Zhao D, Yuan J, Yuan F, Lin S, Yuan J•
PubMed

Enhanced H. pylori Treatment Using a β-Cyclodextrin-Propolis Complex: A Randomized Clinical Trial.

Background Helicobacter pylori infection poses a significant global health burden, with rising antibiotic resistance and treatment‐related side effects highlighting the need for adjunctive therapies. Propolis, a natural resin with known antimicrobial and anti‐inflammatory properties, suffers from poor solubility and bioavailability. This study evaluated a β‐cyclodextrin–propolis complex designed to enhance delivery and therapeutic efficacy in H. pylori‐infected patients. Materials and Methods...

H. Pylori
Mehri A, Pourmoslemi S, Khalilian A, Safari M, Ayubi E•
PubMed

Anti-Helicobacter pylori Activity of Musa 'False Horn' (Musaceae), Syzygium aromaticum (Myrtaceae), Psidium guajava (Myrtaceae), Mangifera indica (Anacardiaceae), and Cymbopogon citratus (Poaceae) and Their Potential to Prevent and Eradicate H. pylori Biofilms.

Objectives The present study evaluated the antimicrobial activity of extracts from five Cameroonian medicinal plants against planktonic forms of Helicobacter pylori isolates and assessed their ability to inhibit biofilm formation and eradicate preformed biofilms. Methods The antimicrobial activity of 15 extracts obtained from Psidium guajava leaves, Mangifera indica leaves, Cymbopogon citratus aerial parts, Musa ‘False Horn’ ripe fruit peelings, and Syzygium aromaticum flower buds was evaluat...

H. Pylori
Almeida KNC, Brigitte KML•
PubMed

Navigating Continuous Glucose Monitoring Adoption: Insights From Hispanic Adults With Insulin-Treated Type 2 Diabetes.

Objective Hispanic individuals are disproportionately affected by type 2 diabetes (T2D) and face access limitations in diabetes technology utilization. Despite proven benefits, continuous glucose monitoring (CGM) use remains low among Hispanic adults with insulin‐treated T2D. This study used a social–ecological model (SEM) framework to identify societal/policy, interpersonal/community, and individual level barriers to CGM access and adoption within this population. Methods Two focus groups we...

Glucose Monitoring
Soliman D, Arevalo G, Galindo RJ, Churba B, Malden KG, Jimenez DE, Pasquel FJ, Baidal DA, Walker AF•
PubMed

Postpartum Glycaemic Phenotype and Continuous Glucose Monitoring at 4-6 Years After Gestational Diabetes Defined by Different Diagnostic Criteria.

Aim To characterise glycaemic outcomes 4–6 years postpartum according to gestational diabetes mellitus (GDM) diagnostic thresholds and evaluate whether continuous glucose monitoring (CGM) identifies differences not captured by conventional clinical measures. Methods Women recruited before and after introduction of WHO GDM criteria were followed at 4 and 6 years postpartum. At each follow‐up, participants underwent oral glucose tolerance testing (OGTT), HbA1c measurement, body composition asse...

Glucose Monitoring
Andersson-Hall U, Kristiansson E, Åberg S, Törnqvist M, Wallenius K, Sengpiel V, Holmäng A•
PubMed

Characterizing Continuous Glucose Monitoring Prescription Patterns Between 2020 and 2024: A Retrospective Study at a Single Primary Care Facility in the United States.

Objective Examine the factors associated with continuous glucose monitoring (CGM) device prescriptions in a primary care facility. Materials and Methods We conducted a retrospective study of 1476 patients with Type 1 and Type 2 diabetes receiving care at a single primary care facility between 2020 and 2024. We examined the associations between receiving a CGM prescription and demographic characteristics, health factors, de‐identified physician information, and insurance status. We conducted u...

Glucose Monitoring
Mkuu R, Rahman P, Rivero-Mendoza D, Donahoo WT, Shenkman E, Ojo D, Lamas MR•

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