Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.
Objective: Hypertension and abnormal circadian blood pressure (BP) rhythm are prevalent in maintenance hemodialysis (MHD) patients, and are closely associated with cardiovascular diseases (CVD) and increased all-cause mortality. Volume overload represents a critical factor in effectively controlling hypertension. Bioelectrical Impedance Analysis (BIA) has been validated as an accurate method for assessing volume status. This study aimed to investigate the predictive value of BIA-derived volume i...
Blood Pressure
Qian Wang, Min Li, Shipeng Shen, Yao Hu, Yongzhe Chen, Changchang Liang, Ke Yu, Ying Li, Yanqing Chi, Lu Bai•
Phyllosphere microbial communities play important roles in plant health, yet the roles of plant defense hormones and coinfections in shaping these communities remain unclear. This study investigated how exogenous application of the plant defense hormone salicylic acid and fungal coinfection influenced microbial communities on leaves of tall fescue. In a factorial experiment, we treated leaves with salicylic acid (at 100 mg/L) or a control solution and inoculated them with one of four inoculation...
Hormone
Julie K. Geyer, Rita L. Grunberg, Charles E. Mitchell•
Diabetes mellitus (DM), a common comorbidity in tuberculosis (TB) patients, can alter the pharmacokinetics (PK) of TB drugs. Additionally, clinical and demographic differences may contribute to interethnic PK variability. However, current WHO-recommended doses for pyrazinamide (PZA) do not account for those factors. We aimed to evaluate factors related to interindividual variability (IIV) and interethnic differences in the PK of PZA between Korean and Indonesian patients with TB. Demographics, c...
Diabetes
Rannissa Puspita Jayanti, Yong-Soon Cho, Soedarsono Soedarsono, Hyo-Jung Kim, Jiyeon Kang, Jehun Kim, Jee Youn Oh, Bo Hyoung Kang, Jick Hwan Ha, Jin-Woo Kim, Ni Made Mertaniasih, Tutik Kusmiati, Ariani Permatasari, Rika Yuliwulandari, Ryunha Kim, Hyeon-Jeong Seong, Jong-Lyul Ghim, Dong-Hyun Kim, Jae-Gook Shin, on behalf of the cPMTb•
Background: Depression is a prevalent psychological challenge during pregnancy, with established links to adverse outcomes like preterm birth (PTB) globally. However, epidemiological data from China’s multiethnic regions are scarce, and experimental evidence supporting a causal relationship remains limited. This study aimed to investigate the association between prenatal depressive symptoms and the risk of PTB in a cohort from Yunnan, China, and to provide supportive evidence using a mouse model...
Obesity is a well-established risk factor for asthma, with genetic factors influencing both conditions. This study investigates the impact of genetic predisposition to increased body mass index (BMI) on adult asthma phenotypes. We recruited 1532 non-asthmatic healthy individuals and 779 adult asthma patients to assess the relationship between BMI-related genetic risk scores (BMI-GRS) and asthma. Among the 85 single nucleotide polymorphisms (SNPs) previously associated with BMI in Japanese popula...
Group psychosocial interventions can be a scalable treatment for depression, anxiety, and post-traumatic stress disorder (PTSD) in low- and middle-income countries (LMICs) but effects are heterogeneous. Little is known about how intervention mechanisms and context interact to generate different outcomes in different populations. We conducted a realist systematic review, combining traditional systematic review methods with analysis of intervention mechanisms and contextual factors to further unde...
Anxiety
Tahir Jokinen, Mujahed Abassi, John Hodsoll, Katie H. Atmore, Chris Bonell, Kelly Rose-Clarke•
Healthcare providers are at a high risk of occupational stress, psychological distress, and mental health issues due to unique job demands. The unprecedented negative impact of the COVID-19 pandemic on healthcare further amplified the risk. We aimed to find out the prevalence of anxiety, depression, and post-traumatic stress disorder (PTSD) in doctors during the COVID-19 pandemic, and explore various associated factors. We conducted a cross-sectional survey among clinicians across tertiary care...
This article investigates the mechanisms influencing health information anxiety among social media users during sudden public health emergencies, aiming to provide insights for managing social media users’ negative emotions in such contexts. By employing literature analysis and case studies and integrating Three-Dimensional Attribution Theory, the factors contributing to health information anxiety are classified into individual, informational, and situational dimensions. Questionnaire data were...
Anxiety
Xiao Wenchang, Yang Xuanhui, Zeng Qun, Cheng Xiao•
Background: Chronic inflammatory bowel diseases, encompassing Crohn’s disease and ulcerative colitis, are characterized by persistent inflammation of the gastrointestinal tract. While traditionally regarded as confined to the gut, the systemic nature of inflammatory bowel disease has been increasingly recognized. The nervous system has garnered particular attention due to molecular and clinical evidence suggesting a potential interplay between inflammatory bowel disease and neurodegenerative dis...
Inflammatory Bowel Disease
Andreas Wolff, Emily Feneberg, Julius Shakhtour, Katja Steiger, Roland M. Schmid, Bernhard Haller, Nya Reinhardt, Moritz Middelhoff, David Schult-Hannemann, Paul Lingor•
Pregnancy and birth can be times of joy, hope, ceremony, and connection for Indigenous women. However, Indigenous maternal health and wellbeing are adversely affected by colonialism and socioeconomic inequities, resulting in otherwise preventable maternal morbidity and mortality. These complex inequities (e.g., marginalization, economic barriers, gendered violence) are highly context specific, and understanding these contexts is essential to inform actions to improve Indigenous maternal health.T...
Pregnancy
Kaitlin Patterson, Shuaib Lwasa, Lea Berrang-Ford, Seungmi Yang, Jan Sargeant, Charity Kesande, Batwa Communities, Sabastian Twesigomwe, Sherilee L. Harper•
Background: The combination of linezolid and opioid drugs such as fentanyl may increase the risk of serotonin syndrome, but its impact on in-hospital mortality is not yet clear. The aim of this study is to investigate the effect of simultaneous use of fentanyl and linezolid on in-hospital mortality in mechanically ventilated patients. Method: Based on the MIMIC-IV database, 3339 patients receiving mechanical ventilation were enrolled and divided into three groups: the group receiving linezolid s...
Fentanyl
Jia-Hui Niu, Xiao-Jiao Cui, Min Chen, Jin-Qi Li, Xiao-Qing Yi•
Stay current
Healthcare information curated for you.
Register to unlock a wealth of healthcare information and medical resources tailored to your healthcare profession.
Cookies on POR. Essential cookies keep the site working. With your permission, optional analytics cookies help us understand how the site is used. We do not send your POR account identity to Google. Read the privacy policy.
