Digestive Enzymes (amylase/cellulase/lipase/maltase/protease/lactase/invertase)
Digestive Enzymes Oral Capsule
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food. Depending on the amount of enzymes in your product, it may be used for indigestion, as a supplement, or as replacement therapy (such as in chronic pancreatitis, cystic fibrosis, cancer of the pancreas, after surgery on the pancreas or gut).
Some supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use. The FDA has not reviewed this product for safety or effectiveness.
Consult your doctor or pharmacist for more details.
Generic name: amylase/cellulase/lipase/maltase/protease/lactase/invertase
Drug class: Digestive Enzymes
Therapeutic class: Gastrointestinal Therapy Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
No indications are available for this drug.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same patient.
Amylase; Pancreatin/Acarbose; Miglitol
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same patient.
MECHANISM OF ACTION: Digestive enzyme preparations such as amylase or pancreatin may break down acarbose(1) and miglitol.(2)
CLINICAL EFFECTS: The concurrent administration digestive enzyme preparations such as amylase or pancreatin may decrease the effectiveness of acarbose(1) and miglitol.(2)
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: The manufacturer of acarbose states that digestive enzymes such as amylase or pancreatin should not be taken concomitantly with acarbose.(1) The manufacturer of miglitol states that digestive enzymes such as amylase or pancreatin should not be taken concomitantly with miglitol.(2)
DISCUSSION: Because digestive enzyme preparations such as amylase or pancreatin may break down acarbose(1) and miglitol(2) and decrease their effectiveness, the manufacturer of acarbose(1) and miglitol(2) state they should not be taken concomitantly with these agents.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
- Gastrointestinal obstruction
- Meconium ileus
- Crohn's disease
- Fibrosing colonopathy
- Gastrointestinal tract surgery
- Gout
- Hyperuricemia
- Short bowel syndrome
Adverse reactions
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Less Frequent
- Abdominal pain with cramps
Rare or Very Rare
- Biliary calculus
- Diarrhea
- Disorder of the digestive system
- Fibrosing colonopathy
- Gastrointestinal obstruction
- Hyperuricemia
- Nausea
Less Frequent
- Abdominal distension
- Cough
- Dizziness
- Flatulence
- Headache disorder
Rare or Very Rare
- Pruritus ani
- Pruritus of skin
- Skin rash
- Urticaria
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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