Niacinamide (niacinamide)
Niacin/Niacinamide (Vitamin B-3) Oral Tablet, Extended Release
Last reviewed · Source: First Databank (FDB) drug data
Overview
Niacin and niacinamide are water-soluble, B complex vitamins.
USES: Niacinamide (nicotinamide) is a form of vitamin B3 (niacin) and is used to prevent and treat niacin deficiency (pellagra). Niacin deficiency can cause diarrhea, confusion (dementia), tongue redness/swelling, and peeling red skin. Niacinamide is often used instead of niacin because it causes fewer side effects (such as flushing).
Unlike niacin, niacinamide does not help correct blood fat levels and cannot be substituted for niacin if you are being treated for a blood fat problem (such as high cholesterol). Niacin deficiency may happen as a result of poor diet, certain medical conditions (such as alcohol abuse, malabsorption syndrome, Hartnup disease), or long-term use of certain medications (such as isoniazid). It is best to get your vitamins from healthy foods.
A multivitamin may be recommended by your doctor instead of niacinamide because poor diet usually causes deficiencies in more than one vitamin. Vitamins help to support the body's ability to make and break down natural substances (metabolism) and are needed for good health.
Generic name: niacinamide
Pronunciation: (NYE-a-SIN-a-mide)
Drug class: Niacin/Niacinamide (Vitamin B-3)
Therapeutic class: Electrolyte Balance-Nutritional Products
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Niacinamide
Indications
The following indications are listed for Niacinamide:
- Niacin Deficiency
- Pellagra
Also known as: Niacin Deficiency Syndrome.
Dosing
No dosing information is available for this tab.
Niacin and niacinamide are administered orally.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Niacin reportedly potentiates the hypotensive effect of ganglionic blocking drugs.
Long-term administration of isoniazid may interfere with the conversion of dietary tryptophan to niacin and increase the requirement of niacin.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Arterial hemorrhage
- Disease of liver
- Increased risk of bleeding due to coagulation disorder
- Peptic ulcer
- Rhabdomyolysis
- Diabetes mellitus
- Gout
- Hypotension
- Unstable angina pectoris
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Abnormal hepatic function tests
More Frequent
- Flatulence
- Flushing
- Heartburn
- Stinging of skin
Less Frequent
- Diarrhea
- Dizziness
- Dry skin
- Exacerbation of peptic ulcer
- Hyperglycemia
- Hyperuricemia
- Hypotension
- Nausea
- Pruritus of skin
- Skin rash
- Tachycardia
- Vomiting
Rare or Very Rare
- Abdominal distension
- Blurred vision
- Cardiac arrhythmia
- Headache disorder
- Skin pigmentation enhancement
- Syncope
Precautions
No enhanced messaging available.
No enhanced messaging available.
Administration of supplementary doses of niacin during pregnancy has not been associated with any adverse effects to the mother or fetus. However, toxicologic studies have not been performed with large doses of niacin, and large doses of the drug should not be used in women who are or may become pregnant unless the possible benefits outweigh the potential risks to the fetus.
Administration of supplementary doses of niacin during lactation has not been associated with any adverse effects to the mother or fetus.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Niacin deficiency | ||
| E52 | ICD10CM | Niacin deficiency [pellagra] |
| Pellagra | ||
| E52 | ICD10CM | Niacin deficiency [pellagra] |
ICD code information from First Databank (FDB).
Formulary status
Search health-plan coverage for this drug by ZIP code.
Choose the first character of a health plan name.
Last reviewed · Source: First Databank (FDB) drug data
On this page
Actions
Sign in to save favorites
Saving this drug requires a free Physicians Office Resource account.