Mydriacyl (tropicamide)
Ophthalmic Cycloplegics/Mydriatics Ophthalmic (EYE) Drops
Last reviewed · Source: First Databank (FDB) drug data
Overview
Tropicamide, a synthetic tertiary amine antimuscarinic, is a mydriatic and cycloplegic.
Tropicamide is an effective mydriatic drug for use prior to examination of the fundus. When complete cycloplegia is necessary, as in measurement of refractive errors, results with tropicamide have been variable. On the basis of some reports, the drug produces adequate cycloplegia only when two instillations are made and when refraction is performed 20-35 minutes following the second instillation.
Other clinical studies confirm rapid recovery but indicate that two instillations of the drug are less satisfactory for cycloplegia than is homatropine or cyclopentolate. Because of its short duration of effect, tropicamide may be useful when a short period of cycloplegia is preferred.
Generic name: tropicamide
Pronunciation: (tro-PICK-uh-mide)
Drug class: Ophthalmic Cycloplegics/Mydriatics
Therapeutic class: Ophthalmic Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Mydriacyl
Indications
The following indications are listed for Mydriacyl:
- Cycloplegia
- Mydriasis
Dosing
To produce mydriasis for funduscopic examination of the eye, 1 or 2 drops of a 0.5% solution of tropicamide may be instilled onto the eye(s) 15-20 minutes before examination. In patients with heavily pigmented irides, higher solution concentrations may be required. To produce cycloplegia for refraction, a 1% solution should be used; 1 or 2 drops of this solution may be instilled onto the eye(s) and repeated in 5 minutes. The examination must be performed within 30 minutes after the second instillation. If the patient is not examined within 20-30 minutes, an additional drop of the 1% solution should be instilled.
When a combination preparation containing tropicamide and hydroxyamphetamine hydrobromide is used to produce mydriasis, 1 or 2 drops of the solution may be instilled onto the eye(s). Patients with lighter irides may experience slightly greater mydriasis than patients with darker irides.
Tropicamide is applied topically to the eye. To avoid excessive systemic absorption, finger pressure should be applied on the lacrimal sac for 1-2 minutes following topical instillation of the solution. Care should be taken to avoid contamination of the solution container.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
- Ocular hypertension
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Acute cognitive impairment
- Behavioral disorders
- Drowsy
- Drug-induced psychosis
- Dyskinesia
- Fatigue
- Flushing
- Hallucinations
- Polydipsia
- Skin rash
- Slurred speech
- Tachycardia
- Xerostomia
Less Frequent
- Blurred vision
- Headache disorder
- Ocular pain
- Photophobia
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies have not been performed with tropicamide. It is not known whether tropicamide can cause fetal harm when administered to pregnant women. Tropicamide should be used during pregnancy only when clearly needed.
It is not known whether tropicamide is distributed into milk. Because many drugs are distributed into milk, tropicamide should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Mydriasis | ||
| Z01.0 | ICD10CM | Encounter for examination of eyes and vision |
| Z01.00 | ICD10CM | Encounter for examination of eyes and vision without abnormal findings |
| Z01.01 | ICD10CM | Encounter for examination of eyes and vision with abnormal findings |
ICD code information from First Databank (FDB).
Formulary status
Search health-plan coverage for this drug by ZIP code.
Choose the first character of a health plan name.
Last reviewed · Source: First Databank (FDB) drug data
On this page
Actions
Sign in to save favorites
Saving this drug requires a free Physicians Office Resource account.