Triesence (triamcinolone acetonide/PF)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Triamcinolone acetonide is a synthetic corticosteroid.

Triamcinolone acetonide is a synthetic glucocorticoid. In animals, triamcinolone acetonide has relatively little mineralocorticoid activity; as a glucocorticoid, the drug is about 8 times more potent than prednisone.

Systemic absorption of triamcinolone acetonide has been shown to be minimal following intranasal administration of the drug. Following intranasal administration of a single 220-mcg dose of triamcinolone acetonide as an aqueous suspension aerosol, mean peak plasma concentrations of about 0.5 ng/mL (range: 0.1-1 ng/mL) were achieved at 1.5 hours following administration.

Generic name: triamcinolone acetonide/PF

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Triesence

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Indications

The following indications are listed for Triesence:

  • Giant Cell Arteritis
  • Ophthalmia Sympathetic
  • Severe Ocular Inflammation
  • Uveitis
  • Vitrectomy Adjunct To Enhance Visualization

Also known as: Cranial Arteritis, Extracranial Arteritis, Giant-Cell Arteritis, Granulomatous Arteritis, Horton's Arteritis, Severe Ophthalmic Inflammation, Sympathetic Ophthalmia, Temporal Arteritis.

Dosing

The nasal aqueous suspension spray pump delivers about 55 mcg of triamcinolone acetonide per metered spray.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

Known hypersensitivity to triamcinolone acetonide or any ingredient in the respective formulations.

Adverse reactions

Adverse effects occurring in at least 2% of adults and children 12 years of age or older receiving triamcinolone acetonide nasal aqueous suspension in clinical trials and more frequently than with placebo included pharyngitis, epistaxis, and increased cough.

Adverse effects occurring in more than 2% of children 4-12 years of age receiving triamcinolone acetonide nasal aqueous suspension in clinical trials and more frequently than with placebo included flu syndrome, increased cough, pharyngitis, bronchitis, dyspepsia, and tooth disorder.

Adverse effects occurring in at least 2% of children 2-5 years of age receiving triamcinolone acetonide nasal aqueous suspension in one study and more frequently than with placebo included headache, pharyngolaryngeal pain, epistaxis, nasopharyngitis, upper abdominal pain, diarrhea, asthma, rash, excoriation, and rhinorrhea.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data