Fluphenazine Hcl (fluphenazine HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Fluphenazine is a phenothiazine antipsychotic agent. The drug is considered a conventional or first-generation antipsychotic agent.
Generic name: fluphenazine HCl
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Fluphenazine Hcl
Indications
The following indications are listed for Fluphenazine Hcl:
- Psychotic Disorder
- Schizophrenia
Also known as: Delusional, Dementia Praecox, Parergasia, Psychosis, Psychotic, Psychotic Disturbance.
Dosing
There is a range of optimum individual dosage requirements of fluphenazine and dosage must be carefully adjusted according to individual requirements and response, using the lowest possible effective dosage. Dosage should be increased more gradually in debilitated, emaciated, or geriatric patients. Because of the risk of adverse reactions associated with cumulative effects of phenothiazines, patients with a history of long-term therapy with fluphenazine and/or other antipsychotic agents should be evaluated periodically to determine whether maintenance dosage could be decreased or drug therapy discontinued. Fluphenazine therapy is best instituted with a low initial dosage, which may be gradually increased, if necessary, until the desired clinical effects are obtained.
Fluphenazine hydrochloride is administered orally or by IM injection. Fluphenazine decanoate is administered by IM or subcutaneous injection, using a dry syringe and needle of at least 21-gauge; use of a wet needle or syringe may cause the solution to become cloudy. When fluphenazine hydrochloride oral concentrate solution is used, the dose should be diluted (e.g., with water; Seven-Up(R); carbonated orange beverage; sodium chloride solution; milk; V-8(R); or pineapple, apricot, prune, orange, tomato, or grapefruit juice) just before administration. (See Chemistry and Stability: Stability.)
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Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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