Nafcillin Sodium (nafcillin sodium)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Nafcillin is a semisynthetic penicillinase-resistant penicillin antibiotic.
Nafcillin shares the uses of other parenteral penicillinase-resistant penicillins (e.g., oxacillin) and generally is used only in the treatment of infections caused by, or suspected of being caused by, susceptible penicillinase-producing staphylococci. For specific information on the uses of nafcillin, see Uses in the Penicillinase-Resistant Penicillins General Statement 8:12.16.12.
Generic name: nafcillin sodium
Pronunciation: (naff-SIL-in)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Nafcillin Sodium
Indications
The following indications are listed for Nafcillin Sodium:
- Acute Staphylococcal Bacterial Sinusitis
- Skin And Skin Structure Infection
- Staphylococcal Meningitis
- Staphylococcal Pneumonia
- Staphylococcal Prosthetic Heart Valve Endocarditis
- Staphylococcus Aureus Endocarditis
- Staphylococcus Aureus Joint Infection
- Staphylococcus Aureus Osteomyelitis
- Staphylococcus Aureus Septicemia
- Staphylococcus Aureus Skin And Skin Structure Infection
- Staphylococcus Infections
Also known as: Acute Sinusitis Due To Staphylococcus Species, Acute Sinusitis Due To Staphylococcus Spp., Endocarditis Due To S. Aureus, Endocarditis Due To Staphylococcus Aureus, Infection Of Skin And/Or Subcutaneous Tissue, Joint Infection Due To Staphylococcus Aureus, Joint Infection Due To Staphylococcus Pyogenes Aureus, Meningitis Due To Staphylococcus Species, Meningitis Due To Staphylococcus Spp., Osteomyelitis Due To Staphylococcus Aureus, Osteomyelitis Due To Staphylococcus Pyogenes Aureus, Pneumonia Due To Staphylococcus Species, Pneumonia Due To Staphylococcus Spp., Prosthetic Heart Valve Endocarditis Due To Staphylococcus, Prosthetic Valvular Endocarditis Due To Staphylococcus, Prosthetic Valvular Staphylococcal Endocarditis, Pve Due To Staphylococcus, Pyogenic Bone Infection Due To Staphylococcus Aureus, Sepsis Due To Staphylococcus Aureus, Septicemia Due To Staph Aureus, Septicemia Due To Staphylococcus Aureus, Skin And Skin Soft Tissue Staphylococcus Aureus Infection, Skin And Soft Tissue Skin Infection, Staphylococcal Infectious Disease, Staphylococcus Species Infection, Staphylococcus Spp. Infection.
Dosing
Dosage of nafcillin sodium is expressed in terms of nafcillin. Dosage of the drug should be adjusted according to the type and severity of infection.
Modification of nafcillin dosage generally is unnecessary in patients with either renal impairment or hepatic impairment alone; however, modification of dosage may be necessary in patients with both severe renal impairment and hepatic impairment.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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Safe use of nafcillin during pregnancy has not been definitely established. Reproduction studies using nafcillin in rats and rabbits have not revealed evidence of impaired fertility or harm to the fetus. Clinical experience with use of penicillins during pregnancy in humans has not revealed evidence of adverse effects on the fetus. However, there are no adequate and controlled studies using penicillinase-resistant penicillins in pregnant women, and nafcillin should be used during pregnancy only when clearly needed.
Because penicillins are distributed into milk, nafcillin should be used with caution in nursing women.
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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