Bronchitol (mannitol)
Cystic Fibrosis - Osmotic Agents Inhaled Inhalation Capsule, With Inhalation Device
Last reviewed · Source: First Databank (FDB) drug data
Overview
Mannitol is an osmotic diuretic.
USES: This medication is used to treat cystic fibrosis. Mannitol may help to improve breathing.
Generic name: mannitol
Pronunciation: (MAN-i-tol)
Drug class: Cystic Fibrosis - Osmotic Agents Inhaled
Therapeutic class: Respiratory Therapy Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Bronchitol
Indications
The following indications are listed for Bronchitol:
- Respiratory Cystic Fibrosis
Also known as: Respiratory Complications Of Cystic Fibrosis.
Dosing
The dosage, concentration of solution, and rate of administration of mannitol vary with the condition being treated and the patient's fluid requirements, urinary output, and response to the drug.
Mannitol injections are administered by IV infusion. An administration set with a filter should be used for infusion of injections containing 20% or more, since mannitol crystals may be present. For transurethral prostatic resection, mannitol irrigation solutions are instilled into the bladder via an indwelling urethral catheter.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Bronchitol 40 Mg Inhale Cap | Maintenance | Inhale the contents of 10 capsules (400 mg) by inhalation route 2 times per day. |
No dosing information is available for this tab.
Drug interactions
Because mannitol increases urinary excretion of lithium, patients being treated with lithium should be observed for possible impairment of response to that drug if they receive mannitol.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- 30 day risk period post-myocardial infarction
- Acute asthma attack
- Aortic aneurysm with dissection
- Arterial aneurysm
- Brain aneurysm
- Cerebrovascular accident
- Exacerbation of chronic obstructive pulmonary disease
- Severe uncontrolled hypertension
- Hemoptysis
- Lower respiratory infection
- Pneumothorax
- Respiratory depression
- Unstable angina pectoris
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Bronchospastic pulmonary disease
- Chest discomfort
- Dyspnea
More Frequent
- Headache disorder
Less Frequent
- Arthralgia
- Cough
- Dizziness
- Fever
- Hemoptysis
- Nausea
- Pain in oropharynx
- Rhinorrhea
- Sore throat
- Vomiting
- Wheezing
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies have not been performed with mannitol. It is also not known whether mannitol can caused fetal harm when administered to pregnant women. Mannitol should be used during pregnancy only when clearly needed.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Respiratory cystic fibrosis | ||
| E84.0 | ICD10CM | Cystic fibrosis with pulmonary manifestations |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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