Drug class

Antidepressant Neuroactive Steroid GABA-A Receptor Modulator

Antidepressant neuroactive steroid GABA-A receptor modulators are a class of psychiatric medications that represent synthetic or endogenous neuroactive steroids designed to treat depressive disorders. Read more about Antidepressant Neuroactive Steroid GABA-A Receptor Modulator

4 drugs in this class 4 manufacturers

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Drugs in Antidepressant Neuroactive Steroid GABA-A Receptor Modulator

Showing 1–4 of 4 drugs

ZULRESSO (brexanolone)

ANTIDEPRESSANT NEUROACTIVE STEROID GABA-A RECEPTOR MODULATOR · POSTPARTUM DEPRESSION
SAGE THERAPEUTI

ZTALMY (ganaxolone)

ANTICONVULSANTS · SEIZURES ASSOCIATED WITH CYCLIN-DEPENDENT KINASE-LIKE 5 DEFICIENCY DISORDER
MARINUS PHARMAC

ZURZUVAE (zuranolone)

ANTIDEPRESSANT NEUROACTIVE STEROID GABA-A RECEPTOR MODULATOR · POSTPARTUM DEPRESSION
BIOGEN-IDEC

ZTALMY (ganaxolone)

ANTICONVULSANTS · SEIZURES ASSOCIATED WITH CYCLIN-DEPENDENT KINASE-LIKE 5 DEFICIENCY DISORDER
MARINUS-IMMEDIC
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About Antidepressant Neuroactive Steroid GABA-A Receptor Modulator.

Antidepressant neuroactive steroid GABA-A receptor modulators are a class of psychiatric medications that represent synthetic or endogenous neuroactive steroids designed to treat depressive disorders.

These agents function primarily as positive allosteric modulators at both synaptic and extrasynaptic GABA-A receptors, enhancing inhibitory central nervous system neurotransmission to help reset dysregulated neural circuits and restore emotional equilibrium.

Clinically exemplified by agents such as zuranolone and brexanolone, this therapeutic class is specifically indicated for the management of postpartum depression in adult patients.