Drug class

Antineoplastic-Anti-SLAMF7 Monoclonal Antibody Agents

Antineoplastic-anti-SLAMF7 monoclonal antibody agents are a specialized class of targeted immunotherapies that selectively bind to signaling lymphocytic activation molecule family member 7 (SLAMF7), a cell-surface glycoprotein highly expressed on myeloma cells and natural killer (NK) cells. Read more about Antineoplastic-Anti-SLAMF7 Monoclonal Antibody Agents

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About Antineoplastic-Anti-SLAMF7 Monoclonal Antibody Agents.

Antineoplastic-anti-SLAMF7 monoclonal antibody agents are a specialized class of targeted immunotherapies that selectively bind to signaling lymphocytic activation molecule family member 7 (SLAMF7), a cell-surface glycoprotein highly expressed on myeloma cells and natural killer (NK) cells.

These agents exert a dual therapeutic mechanism by directly activating endogenous NK cells and tagging malignant plasma cells for antibody-dependent cellular cytotoxicity (ADCC) mediated by immune effector cells.

Represented by elotuzumab, this class is primarily utilized in oncology formularies to treat multiple myeloma, typically in combination with immunomodulatory agents and corticosteroids for patients with relapsed or refractory disease.