PANHEMATIN (hemin)
ANTIPORPHYRIA FACTORS · ACUTE INTERMITTENT PORPHYRIA ·+2
RECORDATI RARE
Drug class
Antiporphyria Factors
"Antiporphyria Factors" is an administrative and formulary classification (such as HIC3 class M0G) rather than a formal FDA established pharmacologic class, primarily encompassing exogenous heme preparations such as intravenous hemin. Read more about Antiporphyria Factors
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"Antiporphyria Factors" is an administrative and formulary classification (such as HIC3 class M0G) rather than a formal FDA established pharmacologic class, primarily encompassing exogenous heme preparations such as intravenous hemin.
Agents within this category function by replenishing the intracellular heme pool, which exerts negative feedback to downregulate delta-aminolevulinic acid synthase 1, the rate-limiting enzyme in heme biosynthesis.
By repressing this pathway, these therapies reduce the toxic accumulation of porphyrins and porphyrin precursors, such as delta-aminolevulinic acid and porphobilinogen.
Consequently, they are indicated for the management and amelioration of recurrent neurovisceral attacks in acute porphyrias, including acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria.
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redsailtechnologies.com
"Antiporphyria Factors" is an administrative and formulary classification (such as HIC3 class M0G) rather than a formal FDA established pharmacologic class, primarily encompassing exogenous heme preparations such as intravenous hemin
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mclarenhealthplan.org
"Antiporphyria Factors" is an administrative and formulary classification (such as HIC3 class M0G) rather than a formal FDA established pharmacologic class, primarily encompassing exogenous heme preparations such as intravenous hemin
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sfhp.org
"Antiporphyria Factors" is an administrative and formulary classification (such as HIC3 class M0G) rather than a formal FDA established pharmacologic class, primarily encompassing exogenous heme preparations such as intravenous hemin Agents within this category function by replenishing the intracellular heme pool, which exerts negative feedback to downregulate delta-aminolevulinic acid synthase 1, the rate-limiting enzyme in heme biosynthesis
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