Drug class
Antipsychotic Diphenylbutylpiperidines
Antipsychotic diphenylbutylpiperidines are a subclass of first-generation (typical) neuroleptic agents chemically derived from butyrophenones, notably including agents such as pimozide, penfluridol, and fluspirilene. Read more about Antipsychotic Diphenylbutylpiperidines
2 drugs in this class 2 manufacturers
Drugs in Antipsychotic Diphenylbutylpiperidines
PIMOZIDE
Antipsychotic diphenylbutylpiperidines are a subclass of first-generation (typical) neuroleptic agents chemically derived from butyrophenones, notably including agents such as pimozide, penfluridol, and fluspirilene.
They exert their primary therapeutic effects through potent antagonism of central postsynaptic dopamine D2 receptors, while also displaying voltage-operated calcium channel antagonist properties and a relatively prolonged duration of action.
Clinically, members of this class are utilized for the management of chronic psychotic disorders, particularly schizophrenia, as well as for the suppression of severe motor and phonic tics in Tourette syndrome.
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nih.gov
Antipsychotic diphenylbutylpiperidines are a subclass of first-generation (typical) neuroleptic agents chemically derived from butyrophenones, notably including agents such as pimozide, penfluridol, and fluspirilene They exert their primary therapeutic effects through potent antagonism of central postsynaptic dopamine D2 receptors, while also displaying voltage-operated calcium channel antagonist properties and a relatively prolonged duration of action Clinically, members of this class are utili...
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drugbank.com
Antipsychotic diphenylbutylpiperidines are a subclass of first-generation (typical) neuroleptic agents chemically derived from butyrophenones, notably including agents such as pimozide, penfluridol, and fluspirilene
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semanticscholar.org
Antipsychotic diphenylbutylpiperidines are a subclass of first-generation (typical) neuroleptic agents chemically derived from butyrophenones, notably including agents such as pimozide, penfluridol, and fluspirilene They exert their primary therapeutic effects through potent antagonism of central postsynaptic dopamine D2 receptors, while also displaying voltage-operated calcium channel antagonist properties and a relatively prolonged duration of action Clinically, members of this class are utili...
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drugcentral.org
They exert their primary therapeutic effects through potent antagonism of central postsynaptic dopamine D2 receptors, while also displaying voltage-operated calcium channel antagonist properties and a relatively prolonged duration of action Clinically, members of this class are utilized for the management of chronic psychotic disorders, particularly schizophrenia, as well as for the suppression of severe motor and phonic tics in Tourette syndrome
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