Drug class

BCG

Bacillus Calmette-Guérin (BCG) refers to a specific biological agent derived from live-attenuated Mycobacterium bovis rather than a broad, multi-drug therapeutic class. Read more about BCG

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Drugs in BCG

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About BCG.

Bacillus Calmette-Guérin (BCG) refers to a specific biological agent derived from live-attenuated Mycobacterium bovis rather than a broad, multi-drug therapeutic class.

Clinically, it functions as an immunomodulatory agent, vaccine, and biological response modifier.

Administered intravesically, BCG triggers an intense local inflammatory response and cell-mediated immune activation that eliminates residual malignant cells and prevents recurrence in non-muscle-invasive bladder cancer, specifically carcinoma in situ and high-grade papillary tumors.

In global public health, it is administered percutaneously or intradermally as an active immunization agent to stimulate protective adaptive immunity against tuberculosis in high-risk populations.