Drug class

Clostridioides (Clostridium) difficile Monoclonal Antibody

The therapeutic class "Clostridioides (Clostridium) difficile Monoclonal Antibody" refers to targeted biological agents engineered to bind and neutralize the pathogenic exotoxins—principally toxin B (TcdB)—secreted by *Clostridioides difficile*. Read more about Clostridioides (Clostridium) difficile Monoclonal Antibody

1 drugs in this class 1 manufacturers

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Drugs in Clostridioides (Clostridium) difficile Monoclonal Antibody

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ZINPLAVA (bezlotoxumab)

CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE MONOCLONAL ANTIBODY · ADJUNCT THERAPY TO PREVENT CLOSTRIDIOIDES DIFFICILE INFECTION (CDI) RECURRENCE
Merck Sharp & Dohme
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About Clostridioides (Clostridium) difficile Monoclonal Antibody.

The therapeutic class "Clostridioides (Clostridium) difficile Monoclonal Antibody" refers to targeted biological agents engineered to bind and neutralize the pathogenic exotoxins—principally toxin B (TcdB)—secreted by *Clostridioides difficile*.

By providing passive immunity and neutralizing toxin activity, these agents inhibit toxin-mediated cellular damage and severe mucosal inflammation in the gastrointestinal tract.

Rather than functioning as bactericidal antibiotics to treat acute infection, drugs in this class are utilized as adjunctive passive immunotherapies administered alongside standard antibacterial regimens to reduce the incidence of recurrent *C.

difficile* infection and associated pseudomembranous colitis in high-risk patients.