Drug class

Dactinomycin

Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics. Read more about Dactinomycin

5 drugs in this class 5 manufacturers

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Drugs in Dactinomycin

Showing 1–5 of 5 drugs

DACTINOMYCIN

DACTINOMYCIN · EWING'S SARCOMA ·+4
X-GEN PHARMACEU

DACTINOMYCIN

DACTINOMYCIN · EWING'S SARCOMA ·+4
HISUN PHARMACEU

DACTINOMYCIN

DACTINOMYCIN · EWING'S SARCOMA ·+4
EUGIA US LLC

DACTINOMYCIN

DACTINOMYCIN · EWING'S SARCOMA ·+4
MEITHEAL PHARMA

DACTINOMYCIN

DACTINOMYCIN · EWING'S SARCOMA ·+4
AURO MEDICS PHA
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About Dactinomycin.

Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics.

It exerts its antineoplastic effects primarily by intercalating between adjacent guanine-cytosine base pairs of DNA, which inhibits RNA synthesis by blocking RNA polymerase elongation and impedes subsequent protein production.

Therapeutically, dactinomycin is used as an essential component of chemotherapy regimens to treat pediatric and adult solid malignancies, including Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia.