Drug class

Glycylcyclines

Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline. Read more about Glycylcyclines

6 drugs in this class 6 manufacturers

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Drugs in Glycylcyclines

Showing 1–6 of 6 drugs

TIGECYCLINE

TETRACYCLINES · HAEMOPHILUS INFLUENZAE PNEUMONIA ·+17
APOTEX CORP

TIGECYCLINE

TETRACYCLINES · HAEMOPHILUS INFLUENZAE PNEUMONIA ·+17
EUGIA US LLC

TIGECYCLINE

TETRACYCLINES · HAEMOPHILUS INFLUENZAE PNEUMONIA ·+17
AMNEAL BIOSCIEN

TIGECYCLINE

TETRACYCLINES · HAEMOPHILUS INFLUENZAE PNEUMONIA ·+17
XELLIA PHARMACE

TIGECYCLINE

TETRACYCLINES · HAEMOPHILUS INFLUENZAE PNEUMONIA ·+17
MEITHEAL PHARMA
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About Glycylcyclines.

Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline.

They function by binding to the 30S ribosomal subunit to block aminoacyl-tRNA from accessing the ribosomal A site, thereby inhibiting bacterial protein synthesis.

Because chemical modifications allow them to overcome common tetracycline resistance mechanisms, such as active drug efflux and ribosomal protection, they remain potent against multidrug-resistant pathogens.

Clinically, glycylcyclines are indicated for treating severe, complex bacterial infections, predominantly complicated intra-abdominal infections, complicated skin and skin-structure infections, and community-acquired bacterial pneumonia.