Drug class
Glycylcyclines
Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline. Read more about Glycylcyclines
6 drugs in this class 6 manufacturers
Drugs in Glycylcyclines
TIGECYCLINE
TIGECYCLINE
TIGECYCLINE
TIGECYCLINE
TIGECYCLINE
Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline.
They function by binding to the 30S ribosomal subunit to block aminoacyl-tRNA from accessing the ribosomal A site, thereby inhibiting bacterial protein synthesis.
Because chemical modifications allow them to overcome common tetracycline resistance mechanisms, such as active drug efflux and ribosomal protection, they remain potent against multidrug-resistant pathogens.
Clinically, glycylcyclines are indicated for treating severe, complex bacterial infections, predominantly complicated intra-abdominal infections, complicated skin and skin-structure infections, and community-acquired bacterial pneumonia.
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fda.gov
Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline They function by binding to the 30S ribosomal subunit to block aminoacyl-tRNA from accessing the ribosomal A site, thereby inhibiting bacterial protein synthesis
-
nih.gov
Glycylcyclines are a class of broad-spectrum antibacterial agents derived from tetracyclines, represented primarily by tigecycline Because chemical modifications allow them to overcome common tetracycline resistance mechanisms, such as active drug efflux and ribosomal protection, they remain potent against multidrug-resistant pathogens
-
fda.gov
They function by binding to the 30S ribosomal subunit to block aminoacyl-tRNA from accessing the ribosomal A site, thereby inhibiting bacterial protein synthesis Clinically, glycylcyclines are indicated for treating severe, complex bacterial infections, predominantly complicated intra-abdominal infections, complicated skin and skin-structure infections, and community-acquired bacterial pneumonia
-
nih.gov
Because chemical modifications allow them to overcome common tetracycline resistance mechanisms, such as active drug efflux and ribosomal protection, they remain potent against multidrug-resistant pathogens Clinically, glycylcyclines are indicated for treating severe, complex bacterial infections, predominantly complicated intra-abdominal infections, complicated skin and skin-structure infections, and community-acquired bacterial pneumonia
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