Drug class

Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib

The phrase "Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib" represents an abbreviated compendial classification string for hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), which are oral hematopoietic agents. Read more about Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib

2 drugs in this class 2 manufacturers

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Drugs in Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib

Showing 1–2 of 2 drugs

JESDUVROQ (daprodustat)

ERYTHROPOIESIS-STIMULATING AGENTS · ANEMIA IN HEMODIALYSIS-DEPENDENT CHRONIC KIDNEY DISEASE
GSK

VAFSEO (vadadustat)

ERYTHROPOIESIS-STIMULATING AGENTS · ANEMIA IN HEMODIALYSIS-DEPENDENT CHRONIC KIDNEY DISEASE
AKEBIA THERAPEU
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About Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib.

The phrase "Hematopoietic-Hypoxia Inducible Factor Prolyl Hydroxyl Inhib" represents an abbreviated compendial classification string for hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), which are oral hematopoietic agents.

These drugs reversibly inhibit prolyl hydroxylase domain enzymes to prevent the degradation of hypoxia-inducible factor-alpha, thereby mimicking the cellular response to hypoxia and stimulating endogenous erythropoietin production alongside enhanced iron absorption and mobilization.

In clinical practice and regulatory evaluations, this therapeutic class is primarily indicated for treating anemia associated with chronic kidney disease, particularly in adults undergoing maintenance dialysis.