Drug class

Hepatitis D - NTCP inhibitor

Hepatitis D – NTCP inhibitors, formally categorized by regulatory authorities as sodium taurocholate co-transporting polypeptide (NTCP)–directed hepatitis delta virus attachment or entry inhibitors, are a class of targeted antiviral agents. Read more about Hepatitis D - NTCP inhibitor

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About Hepatitis D - NTCP inhibitor.

Hepatitis D – NTCP inhibitors, formally categorized by regulatory authorities as sodium taurocholate co-transporting polypeptide (NTCP)–directed hepatitis delta virus attachment or entry inhibitors, are a class of targeted antiviral agents.

Represented by bulevirtide, these agents work by binding to the NTCP receptor on the surface of hepatocytes, preventing the pre-S1 domain of the viral envelope protein from docking and thereby blocking de novo viral entry into liver cells.

This therapeutic drug class is indicated specifically for the treatment of chronic hepatitis delta virus infection in adults with compensated liver disease.