Drug class

Interleukin 2

Interleukin-2 refers primarily to an endogenous cytokine and a specific biological active ingredient rather than a broad, formal therapeutic drug class, though it represents a foundational category of cytokine-based cancer immunotherapies. Read more about Interleukin 2

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About Interleukin 2.

Interleukin-2 refers primarily to an endogenous cytokine and a specific biological active ingredient rather than a broad, formal therapeutic drug class, though it represents a foundational category of cytokine-based cancer immunotherapies.

Formulated therapeutically as recombinant human interleukin-2 (such as aldesleukin), it binds cell-surface interleukin-2 receptors to stimulate the proliferation, differentiation, and cytolytic activity of cytotoxic T lymphocytes and natural killer cells.

Recombinant interleukin-2 therapy is primarily indicated for the treatment of adults with metastatic renal cell carcinoma and metastatic melanoma, and it is also utilized to support adoptive cellular immunotherapies.