Drug class

Methanol or Ethylene Glycol Poisoning Antidote

The therapeutic class of methanol or ethylene glycol poisoning antidotes consists of agents specifically indicated to prevent and manage life-threatening toxic alcohol ingestion. Read more about Methanol or Ethylene Glycol Poisoning Antidote

4 drugs in this class 4 manufacturers

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Drugs in Methanol or Ethylene Glycol Poisoning Antidote

Showing 1–4 of 4 drugs

FOMEPIZOLE

METHANOL OR ETHYLENE GLYCOL POISONING ANTIDOTE · ETHYLENE GLYCOL TOXICITY ·+1
MYLAN INSTITUTI

FOMEPIZOLE

METHANOL OR ETHYLENE GLYCOL POISONING ANTIDOTE · ETHYLENE GLYCOL TOXICITY ·+1
American Regent

FOMEPIZOLE

METHANOL OR ETHYLENE GLYCOL POISONING ANTIDOTE · ETHYLENE GLYCOL TOXICITY ·+1
ZYDUS PHARMACEU

FOMEPIZOLE

METHANOL OR ETHYLENE GLYCOL POISONING ANTIDOTE · ETHYLENE GLYCOL TOXICITY ·+1
SAGENT PHARMACE
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About Methanol or Ethylene Glycol Poisoning Antidote.

The therapeutic class of methanol or ethylene glycol poisoning antidotes consists of agents specifically indicated to prevent and manage life-threatening toxic alcohol ingestion.

These agents, primarily fomepizole and pharmaceutical-grade ethanol, function by competitively inhibiting the enzyme alcohol dehydrogenase, which is responsible for the initial rate-limiting oxidation of the parent alcohols.

By halting this enzymatic conversion, the antidotes block the accumulation of cytotoxic and acidifying downstream metabolites, such as formic acid from methanol and glycolic or oxalic acid from ethylene glycol.

Consequently, they serve a vital role in medical toxicology to protect against severe high anion gap metabolic acidosis, visual impairment or blindness, acute renal failure, and fatal central nervous system depression.