Drug class

Ophthalmic Anticholinesterase Miotics

Ophthalmic anticholinesterase miotics are a class of topical parasympathomimetic agents that indirectly induce pupillary constriction and ciliary muscle contraction by inhibiting acetylcholinesterase, thereby preventing the enzymatic breakdown of endogenous acetylcholine in ocular tissues. Read more about Ophthalmic Anticholinesterase Miotics

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About Ophthalmic Anticholinesterase Miotics.

Ophthalmic anticholinesterase miotics are a class of topical parasympathomimetic agents that indirectly induce pupillary constriction and ciliary muscle contraction by inhibiting acetylcholinesterase, thereby preventing the enzymatic breakdown of endogenous acetylcholine in ocular tissues.

By contracting the ciliary body and iris sphincter, these medications widen the trabecular meshwork spaces to enhance aqueous humor outflow and lower intraocular pressure.

Clinically, agents in this class—such as echothiophate iodide—are primarily indicated for reducing intraocular pressure in open-angle glaucoma and secondary glaucomas, as well as for the management of accommodative esotropia.