PROTOPAM CHLORIDE (pralidoxime chloride)
ORGANOPHOSPHATE POISONING ANTIDOTE · CHOLINESTERASE INHIBITORS TOXICITY ·+3
Baxter Healthcare Company
Drug class
Organophosphate Poisoning Antidote
The term "organophosphate poisoning antidote" describes a functional therapeutic category rather than a single distinct pharmacological class, comprising agents used to counter acute toxicity from organophosphate pesticides and chemical nerve agents. Read more about Organophosphate Poisoning Antidote
3 drugs in this class 2 manufacturers
Drugs in Organophosphate Poisoning Antidote
PRALIDOXIME CHLORIDE
ORGANOPHOSPHATE POISONING ANTIDOTE · CHOLINESTERASE INHIBITORS TOXICITY ·+3
MERIDIAN MEDICA
DUODOTE (pralidoxime chloride/atropine sulfate)
ORGANOPHOSPHATE POISONING ANTIDOTE · ORGANOPHOSPHOROUS OVERDOSE ·+2
MERIDIAN MEDICA
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The term "organophosphate poisoning antidote" describes a functional therapeutic category rather than a single distinct pharmacological class, comprising agents used to counter acute toxicity from organophosphate pesticides and chemical nerve agents.
This grouping primarily consists of antimuscarinic agents such as atropine and acetylcholinesterase reactivators known as oximes, most notably pralidoxime.
Antimuscarinic therapy competitively antagonizes excess acetylcholine at muscarinic receptor sites to control life-threatening bronchorrhea and bronchospasm, while oximes work to dephosphorylate and reactivate acetylcholinesterase at neuromuscular junctions before irreversible enzyme binding occurs.
These agents are indicated for emergency management of cholinergic crisis and neuromuscular dysfunction resulting from toxic agricultural pesticide exposure or chemical warfare agent poisoning.
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nih.gov
The term "organophosphate poisoning antidote" describes a functional therapeutic category rather than a single distinct pharmacological class, comprising agents used to counter acute toxicity from organophosphate pesticides and chemical nerve agents Antimuscarinic therapy competitively antagonizes excess acetylcholine at muscarinic receptor sites to control life-threatening bronchorrhea and bronchospasm, while oximes work to dephosphorylate and reactivate acetylcholinesterase at neuromuscular ju...
-
nih.gov
The term "organophosphate poisoning antidote" describes a functional therapeutic category rather than a single distinct pharmacological class, comprising agents used to counter acute toxicity from organophosphate pesticides and chemical nerve agents
-
nih.gov
This grouping primarily consists of antimuscarinic agents such as atropine and acetylcholinesterase reactivators known as oximes, most notably pralidoxime
-
nih.gov
This grouping primarily consists of antimuscarinic agents such as atropine and acetylcholinesterase reactivators known as oximes, most notably pralidoxime
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