XENLETA (lefamulin acetate)
PLEUROMUTILIN DERIVATIVES, SYSTEMIC · COMMUNITY ACQUIRED BACTERIAL PNEUMONIA
NABRIVA THERAPE
Drug class
Pleuromutilin Derivatives, Systemic
Systemic pleuromutilin derivatives are a class of semisynthetic antibacterial agents formulated for oral and intravenous administration, distinguished clinically from earlier topical pleuromutilins. Read more about Pleuromutilin Derivatives, Systemic
2 drugs in this class 1 manufacturers
Drugs in Pleuromutilin Derivatives, Systemic
XENLETA (lefamulin acetate)
PLEUROMUTILIN DERIVATIVES, SYSTEMIC · COMMUNITY ACQUIRED BACTERIAL PNEUMONIA
NABRIVA THERAPE
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Systemic pleuromutilin derivatives are a class of semisynthetic antibacterial agents formulated for oral and intravenous administration, distinguished clinically from earlier topical pleuromutilins.
They exert their therapeutic effect by inhibiting bacterial protein synthesis, selectively binding to the peptidyl transferase center of the 50S ribosomal subunit to prevent the correct positioning of transfer RNA and disrupt peptide bond formation.
This unique target interaction minimizes cross-resistance with other existing antibiotic classes.
Within systemic human pharmacotherapy, this class—principally represented by lefamulin—is primarily indicated for the treatment of adults with community-acquired bacterial pneumonia caused by susceptible typical and atypical respiratory pathogens.
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fda.gov
Systemic pleuromutilin derivatives are a class of semisynthetic antibacterial agents formulated for oral and intravenous administration, distinguished clinically from earlier topical pleuromutilins They exert their therapeutic effect by inhibiting bacterial protein synthesis, selectively binding to the peptidyl transferase center of the 50S ribosomal subunit to prevent the correct positioning of transfer RNA and disrupt peptide bond formation
-
fda.gov
Systemic pleuromutilin derivatives are a class of semisynthetic antibacterial agents formulated for oral and intravenous administration, distinguished clinically from earlier topical pleuromutilins
-
nih.gov
Systemic pleuromutilin derivatives are a class of semisynthetic antibacterial agents formulated for oral and intravenous administration, distinguished clinically from earlier topical pleuromutilins Within systemic human pharmacotherapy, this class—principally represented by lefamulin—is primarily indicated for the treatment of adults with community-acquired bacterial pneumonia caused by susceptible typical and atypical respiratory pathogens
-
fda.gov
They exert their therapeutic effect by inhibiting bacterial protein synthesis, selectively binding to the peptidyl transferase center of the 50S ribosomal subunit to prevent the correct positioning of transfer RNA and disrupt peptide bond formation
-
drugbank.com
They exert their therapeutic effect by inhibiting bacterial protein synthesis, selectively binding to the peptidyl transferase center of the 50S ribosomal subunit to prevent the correct positioning of transfer RNA and disrupt peptide bond formation This unique target interaction minimizes cross-resistance with other existing antibiotic classes Within systemic human pharmacotherapy, this class—principally represented by lefamulin—is primarily indicated for the treatment of adults with community-a...
-
nih.gov
This unique target interaction minimizes cross-resistance with other existing antibiotic classes
-
fda.gov
Within systemic human pharmacotherapy, this class—principally represented by lefamulin—is primarily indicated for the treatment of adults with community-acquired bacterial pneumonia caused by susceptible typical and atypical respiratory pathogens
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