Typhoid Vaccine

Typhoid vaccines comprise a class of immunobiological agents formulated to stimulate active immunity against enteric fever caused by the bacterium *Salmonella enterica* serovar Typhi Depending on the specific formulation—such as oral live-attenuated strains, parenteral capsular Vi polysaccharides, or protein-conjugated Vi polysaccharides—these vaccines function by inducing protective systemic humoral, mucosal, or T-cell–dependent immune responses against bacterial surface antigens Clinically, th...

Typhoid vaccines comprise a class of immunobiological agents formulated to stimulate active immunity against enteric fever caused by the bacterium *Salmonella enterica* serovar Typhi Clinically, they are indicated for the prevention of typhoid fever in individuals traveling to endemic areas, household contacts of documented chronic carriers, and laboratory personnel routinely exposed to *S. Typhi*, as well as for mass immunization programs in regions with significant disease burden

Depending on the specific formulation—such as oral live-attenuated strains, parenteral capsular Vi polysaccharides, or protein-conjugated Vi polysaccharides—these vaccines function by inducing protective systemic humoral, mucosal, or T-cell–dependent immune responses against bacterial surface antigens Clinically, they are indicated for the prevention of typhoid fever in individuals traveling to endemic areas, household contacts of documented chronic carriers, and laboratory personnel routinely e...