Gentamicin Sulfate (gentamicin sulfate)
Ophthalmic Antibacterials Ophthalmic (Eye) Drops
Last reviewed · Source: First Databank (FDB) drug data
Overview
Gentamicin is an aminoglycoside antibiotic.
USES: This medication is used to treat bacterial infections (such as blepharitis, conjunctivitis) of the eye and the skin around the eyes (such as eyelids). It is also used to prevent infection after eye injury or surgery. It belongs to a class of drugs known as aminoglycoside antibiotics.
Gentamicin works by killing the bacteria. This medication treats only bacterial eye infections. It will not work for other types of eye infections.
Using any antibiotic when it is not needed can cause it to not work for future infections.
Generic name: gentamicin sulfate
Pronunciation: (jen-ta-MYE-sin)
Drug class: Ophthalmic Antibacterials
Therapeutic class: Ophthalmic Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Gentamicin Sulfate
Indications
The following indications are listed for Gentamicin Sulfate:
- Bacterial Blepharitis
- Bacterial Conjunctivitis
- Bacterial Keratitis
- Blepharoconjunctivitis
- Dacryocystitis
- Meibomianitis
Also known as: Inflammation Of A Meibomian Gland Of The Eyelid, Inflammation Of The Conjunctiva Due To Bacteria, Lacrimal Sac Inflammation.
Dosing
Dosage of gentamicin sulfate is expressed in terms of the base.
Dosage of fixed-combination preparations containing gentamicin sulfate and prednisolone acetate is expressed in terms of gentamicin base and the prednisolone salt.
No dosing information is available for this tab.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Gentamicin 0.3% Eye Drop | Maintenance | Instill 1 drop into affected eye(s) by ophthalmic route every 4 hours. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Gentamicin 0.3% Eye Drop | Maintenance | Instill 1 drop into affected eye(s) by ophthalmic route every 4 hours. |
| Gentamicin 3 Mg/Ml Eye Drop | Maintenance | Instill 1 drop into affected eye(s) by ophthalmic route every 4 hours. |
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Mt-RNr1 increased risk of aminoglycoside-induced hearing loss
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Ocular inflammation
- Ocular itching
- Ocular pain
- Ocular redness
- Pruritus of skin
Less Frequent
- Blurred vision
- Conjunctival hyperemia
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies indicate that gentamicin can depress body weights, kidney weights, and median glomerular counts in newborn rats when given systemically to pregnant rats in daily doses approximately 500 times the maximum recommended ophthalmic human dose.
There are no adequate and well-controlled studies using gentamicin ophthalmic preparations in pregnant women. Gentamicin ophthalmic preparations, including fixed-combination preparations containing gentamicin and prednisolone acetate, should be during pregnancy only if potential benefits justify potential risks to the fetus.
Systemic gentamicin is distributed into milk.
A decision should be made whether to discontinue nursing or discontinue gentamicin ophthalmic preparations, taking into account the importance of the drug to the woman.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Bacterial blepharitis | ||
| H01.0 | ICD10CM | Blepharitis |
| H01.00 | ICD10CM | Unspecified blepharitis |
| H01.001 | ICD10CM | Unspecified blepharitis right upper eyelid |
| H01.002 | ICD10CM | Unspecified blepharitis right lower eyelid |
| H01.003 | ICD10CM | Unspecified blepharitis right eye, unspecified eyelid |
| H01.004 | ICD10CM | Unspecified blepharitis left upper eyelid |
| H01.005 | ICD10CM | Unspecified blepharitis left lower eyelid |
| H01.006 | ICD10CM | Unspecified blepharitis left eye, unspecified eyelid |
| H01.009 | ICD10CM | Unspecified blepharitis unspecified eye, unspecified eyelid |
| H01.00A | ICD10CM | Unspecified blepharitis right eye, upper and lower eyelids |
| H01.00B | ICD10CM | Unspecified blepharitis left eye, upper and lower eyelids |
| H01.01 | ICD10CM | Ulcerative blepharitis |
| H01.011 | ICD10CM | Ulcerative blepharitis right upper eyelid |
| H01.012 | ICD10CM | Ulcerative blepharitis right lower eyelid |
| H01.013 | ICD10CM | Ulcerative blepharitis right eye, unspecified eyelid |
| H01.014 | ICD10CM | Ulcerative blepharitis left upper eyelid |
| H01.015 | ICD10CM | Ulcerative blepharitis left lower eyelid |
| H01.016 | ICD10CM | Ulcerative blepharitis left eye, unspecified eyelid |
| H01.019 | ICD10CM | Ulcerative blepharitis unspecified eye, unspecified eyelid |
| H01.01A | ICD10CM | Ulcerative blepharitis right eye, upper and lower eyelids |
| H01.01B | ICD10CM | Ulcerative blepharitis left eye, upper and lower eyelids |
| H01.02 | ICD10CM | Squamous blepharitis |
| H01.021 | ICD10CM | Squamous blepharitis right upper eyelid |
| H01.022 | ICD10CM | Squamous blepharitis right lower eyelid |
| H01.023 | ICD10CM | Squamous blepharitis right eye, unspecified eyelid |
| H01.024 | ICD10CM | Squamous blepharitis left upper eyelid |
| H01.025 | ICD10CM | Squamous blepharitis left lower eyelid |
| H01.026 | ICD10CM | Squamous blepharitis left eye, unspecified eyelid |
| H01.029 | ICD10CM | Squamous blepharitis unspecified eye, unspecified eyelid |
| H01.02A | ICD10CM | Squamous blepharitis right eye, upper and lower eyelids |
| H01.02B | ICD10CM | Squamous blepharitis left eye, upper and lower eyelids |
| Bacterial conjunctivitis | ||
| H10.02 | ICD10CM | Other mucopurulent conjunctivitis |
| H10.021 | ICD10CM | Other mucopurulent conjunctivitis, right eye |
| H10.022 | ICD10CM | Other mucopurulent conjunctivitis, left eye |
| H10.023 | ICD10CM | Other mucopurulent conjunctivitis, bilateral |
| H10.029 | ICD10CM | Other mucopurulent conjunctivitis, unspecified eye |
| H10.3 | ICD10CM | Unspecified acute conjunctivitis |
| H10.30 | ICD10CM | Unspecified acute conjunctivitis, unspecified eye |
| H10.31 | ICD10CM | Unspecified acute conjunctivitis, right eye |
| H10.32 | ICD10CM | Unspecified acute conjunctivitis, left eye |
| H10.33 | ICD10CM | Unspecified acute conjunctivitis, bilateral |
| Bacterial keratitis | ||
| H16.10 | ICD10CM | Unspecified superficial keratitis |
| H16.101 | ICD10CM | Unspecified superficial keratitis, right eye |
| H16.102 | ICD10CM | Unspecified superficial keratitis, left eye |
| H16.103 | ICD10CM | Unspecified superficial keratitis, bilateral |
| H16.109 | ICD10CM | Unspecified superficial keratitis, unspecified eye |
| H16.32 | ICD10CM | Diffuse interstitial keratitis |
| H16.321 | ICD10CM | Diffuse interstitial keratitis, right eye |
| H16.322 | ICD10CM | Diffuse interstitial keratitis, left eye |
| H16.323 | ICD10CM | Diffuse interstitial keratitis, bilateral |
| H16.329 | ICD10CM | Diffuse interstitial keratitis, unspecified eye |
| H16.39 | ICD10CM | Other interstitial and deep keratitis |
| H16.391 | ICD10CM | Other interstitial and deep keratitis, right eye |
| H16.392 | ICD10CM | Other interstitial and deep keratitis, left eye |
| H16.393 | ICD10CM | Other interstitial and deep keratitis, bilateral |
| H16.399 | ICD10CM | Other interstitial and deep keratitis, unspecified eye |
| H16.8 | ICD10CM | Other keratitis |
| Blepharoconjunctivitis | ||
| H10.5 | ICD10CM | Blepharoconjunctivitis |
| H10.50 | ICD10CM | Unspecified blepharoconjunctivitis |
| H10.501 | ICD10CM | Unspecified blepharoconjunctivitis, right eye |
| H10.502 | ICD10CM | Unspecified blepharoconjunctivitis, left eye |
| H10.503 | ICD10CM | Unspecified blepharoconjunctivitis, bilateral |
| H10.509 | ICD10CM | Unspecified blepharoconjunctivitis, unspecified eye |
| H10.52 | ICD10CM | Angular blepharoconjunctivitis |
| H10.521 | ICD10CM | Angular blepharoconjunctivitis, right eye |
| H10.522 | ICD10CM | Angular blepharoconjunctivitis, left eye |
| H10.523 | ICD10CM | Angular blepharoconjunctivitis, bilateral |
| H10.529 | ICD10CM | Angular blepharoconjunctivitis, unspecified eye |
| Dacryocystitis | ||
| H04.30 | ICD10CM | Unspecified dacryocystitis |
| H04.301 | ICD10CM | Unspecified dacryocystitis of right lacrimal passage |
| H04.302 | ICD10CM | Unspecified dacryocystitis of left lacrimal passage |
| H04.303 | ICD10CM | Unspecified dacryocystitis of bilateral lacrimal passages |
| H04.309 | ICD10CM | Unspecified dacryocystitis of unspecified lacrimal passage |
| H04.31 | ICD10CM | Phlegmonous dacryocystitis |
| H04.311 | ICD10CM | Phlegmonous dacryocystitis of right lacrimal passage |
| H04.312 | ICD10CM | Phlegmonous dacryocystitis of left lacrimal passage |
| H04.313 | ICD10CM | Phlegmonous dacryocystitis of bilateral lacrimal passages |
| H04.319 | ICD10CM | Phlegmonous dacryocystitis of unspecified lacrimal passage |
| H04.32 | ICD10CM | Acute dacryocystitis |
| H04.321 | ICD10CM | Acute dacryocystitis of right lacrimal passage |
| H04.322 | ICD10CM | Acute dacryocystitis of left lacrimal passage |
| H04.323 | ICD10CM | Acute dacryocystitis of bilateral lacrimal passages |
| H04.329 | ICD10CM | Acute dacryocystitis of unspecified lacrimal passage |
| H04.41 | ICD10CM | Chronic dacryocystitis |
| H04.411 | ICD10CM | Chronic dacryocystitis of right lacrimal passage |
| H04.412 | ICD10CM | Chronic dacryocystitis of left lacrimal passage |
| H04.413 | ICD10CM | Chronic dacryocystitis of bilateral lacrimal passages |
| H04.419 | ICD10CM | Chronic dacryocystitis of unspecified lacrimal passage |
| P39.1 | ICD10CM | Neonatal conjunctivitis and dacryocystitis |
| Meibomianitis | ||
| H00.02 | ICD10CM | Hordeolum internum |
| H00.021 | ICD10CM | Hordeolum internum right upper eyelid |
| H00.022 | ICD10CM | Hordeolum internum right lower eyelid |
| H00.023 | ICD10CM | Hordeolum internum right eye, unspecified eyelid |
| H00.024 | ICD10CM | Hordeolum internum left upper eyelid |
| H00.025 | ICD10CM | Hordeolum internum left lower eyelid |
| H00.026 | ICD10CM | Hordeolum internum left eye, unspecified eyelid |
| H00.029 | ICD10CM | Hordeolum internum unspecified eye, unspecified eyelid |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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