Promethazine Hcl (promethazine HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used with other medication to treat severe allergic reactions (anaphylaxis) and reactions to blood products. It may also be used to treat milder allergic reactions when you cannot take promethazine by mouth.
It may also be used to help you feel sleepy/relaxed before and after surgery, during other procedures, or during labor and delivery. It may also be used to help certain opioid pain relievers (such as meperidine) work better. Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as acetylcholine) and by acting directly on certain parts of the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as slow/shallow breathing). See also Warning section.
Generic name: promethazine HCl
Pronunciation: (pro-METH-uh-zeen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Promethazine Hcl
Indications
The following indications are listed for Promethazine Hcl:
- Allergic Reaction
- Anaphylaxis Adjunct
- Apprehension
- General Anesthesia Adjunct
- Motion Sickness
- Nausea And Vomiting
- Pain Treatment Adjunct
- Prevention Of Post-Operative Nausea And Vomiting
- Sedation As Adjunct To Anesthesia
- Sedation In Obstetrics
- Transfusion Reaction Urticaria
Also known as: Adjunct General Anesthesia, Adjunct Medication Therapy For Anaphylactic Reaction, Adjunct Medication Therapy For Anaphylaxis, Adjunct Medication Therapy For Pain, Adjunct Medication Treatment For Pain, Adjunct Sedation, Allergic Reaction To Blood Or Plasma, Allergic Transfusion Reaction, Apprehensive, Obstetric Sedation, Postop Nausea And Vomiting Prophylaxis, Postoperative Nausea And Vomiting Prophylaxis, Riders' Vertigo, Urticarial Transfusion Reaction.
Dosing
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Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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ICD codes
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Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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