Cyclobenzaprine Hcl Er (cyclobenzaprine HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Cyclobenzaprine is a centrally acting skeletal muscle relaxant.
USES: Cyclobenzaprine is used short-term to treat muscle spasms. It is usually used along with rest and physical therapy. It works by helping to relax the muscles.
This medication is not recommended for use in older adults because they may be at greater risk for side effects while using this drug. Ask the doctor or pharmacist for details.
Generic name: cyclobenzaprine HCl
Pronunciation: (sye-klo-BENZ-uh-preen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Cyclobenzaprine Hcl Er
Indications
The following indications are listed for Cyclobenzaprine Hcl Er:
- Muscle Spasm
Also known as: Involuntary Muscle Contraction, Muscle Spasticity, Skeletal Muscle Spasm, Spasticity.
Dosing
The manufacturer of cyclobenzaprine hydrochloride immediate-release tablets states that less frequent dosing should be considered in geriatric patients, initiating cyclobenzaprine hydrochloride with a 5-mg dose and titrating upward slowly.
Cyclobenzaprine extended-release capsules are not recommended for use in geriatric patients.
The manufacturer of cyclobenzaprine hydrochloride tablets states that less frequent dosing should be considered in patients with mild hepatic impairment, beginning with a 5-mg dose and slowly titrating upward. Use of the drug is not recommended in patients with moderate or severe hepatic impairment.
Because of limited dosing flexibility, the manufacturer of the extended-release capsules states that this dosage form is not recommended for use in patients with hepatic impairment.
Cyclobenzaprine is administered orally (as immediate-release tablets or extended-release capsules).
The extended-release capsules should be swallowed intact. Alternatively, the capsules may be opened and the contents sprinkled onto a tablespoon of applesauce and consumed immediately without chewing; foods other than applesauce have not been tested and should not be used. Following administration, patients should rinse their mouth to ensure that all the capsule contents have been swallowed. Any unused portion of the capsules should be discarded.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants and shares the drug interaction potentials of these drugs. For additional information on potential drug interactions of tricyclic antidepressants, see Drug Interactions in the Tricyclic Antidepressants General Statement 28:16.04.28.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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No enhanced messaging available.
Reproduction studies in animals using cyclobenzaprine doses up to 20 times the human dose have not revealed evidence of harm to the fetus. There are no adequate and controlled studies to date using cyclobenzaprine in pregnant women, and the drug should be used during pregnancy only when clearly needed.
It is not known whether cyclobenzaprine is distributed into milk; however, the drug is distributed into milk in rats. Because some related tricyclic antidepressants are distributed into milk, cyclobenzaprine should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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