Tobramycin-Vancomycin (tobramycin sulfate/vancomycin HCl)
Ophthalmic Antibacterials Ophthalmic (Eye) Drops
Last reviewed · Source: First Databank (FDB) drug data
Overview
Tobramycin is an aminoglycoside antibiotic.
Generic name: tobramycin sulfate/vancomycin HCl
Drug class: Ophthalmic Antibacterials
Therapeutic class: Ophthalmic Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Tobramycin-Vancomycin
Indications
No indications are available for this drug.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Ocular inflammation
- Ocular itching
- Ocular redness
Rare or Very Rare
- Anaphylaxis
- Erythema multiforme
- Hypersensitivity drug reaction
- Punctate keratitis
- Stevens-johnson syndrome
Less Frequent
- Blurred vision
- Conjunctival hyperemia
- Ocular irritation
- Ocular pain
Rare or Very Rare
- Eyelid edema
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies using systemic tobramycin dosages up to 33 times the usual human systemic dosage have not revealed evidence of impaired fertility or harm to the fetus.
There are no controlled studies to date using tobramycin ophthalmic preparations in pregnant women.
Tobramycin ophthalmic ointment and ophthalmic solution should be used during pregnancy only if clearly needed.
Fixed-combination ophthalmic preparations containing tobramycin and a corticosteroid (i.e., dexamethasone or loteprednol etabonate) should be used during pregnancy only if potential benefits justify potential risks to the fetus.
A decision should be made whether to discontinue nursing or discontinue tobramycin ophthalmic preparations, taking into account the importance of the drug to the woman.
The manufacturers state that caution is advised if fixed-combination ophthalmic preparations containing tobramycin and a corticosteroid are used in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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