Opzelura (vinblastine sulfate)
Janus Kinase (JAK) Inhibitors Topical Cream (GRAM)
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: Vinblastine is used to treat cancer. It works by slowing or stopping the growth of cancer cells.
Generic name: vinblastine sulfate
Pronunciation: (vin-BLAS-teen)
Drug class: Janus Kinase (JAK) Inhibitors
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Opzelura
Indications
The following indications are listed for Opzelura:
- Carcinoma Of Breast
- Gestational Trophoblastic Neoplasia
- Hodgkin's Lymphoma
- Kaposi's Sarcoma
- Letterer-Siwe Disease
- Malignant Tumor Of Testis
- Metastatic Breast Carcinoma
- Mycosis Fungoides
- Non-Hodgkin's Lymphoma
Also known as: Advanced Breast Carcinoma, Anemia Lymphatica, Breast Carcinoma, Endotheliosarcoma, Hodgkin's Disease, Malignancy Of Testis, Malignant Neoplasm Of Testis, Metastatic Breast Cancer, Metastatic Malignancy Of Breast, Metastatic Malignant Neoplasm Of Breast, Metastatic Malignant Tumor Of Breast, Multiple Idiopathic Hemorrhagic Sarcoma, Non-Hodgkin's Type Lymphoma, Nonlipid Histiocytosis, Testicle Cancer, Testicular Cancer, Trophoblastic Neoplasm.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Opzelura 1.5% Cream | Maintenance | Apply a thin layer to the affected area(s) by topical route 2 times per day (do not exceed 60 grams per week). |
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Lactation
- Thromboembolic disorder
- Active tuberculosis
- Anemia
- Atherosclerotic cardiovascular disease
- Cerebrovascular accident
- Herpes zoster
- Malignancy
- Malignant lymphoma
- Neutropenic disorder
- Opportunistic fungal infection
- Opportunistic viral infection
- Severe infection
- Thrombocytopenic disorder
- Basal cell carcinoma of skin
- Squamous cell carcinoma
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Infection
Rare or Very Rare
- Anemia
- Herpes zoster
- Hypoglycemic disorder
- Neutropenic disorder
- Thrombocytopenic disorder
- Thromboembolic disorder
More Frequent
- Bronchitis
- Diarrhea
- Eosinophilia
- Folliculitis
- Infection of ear
- Pharyngitis
- Rhinorrhea
- Tonsillitis
- Upper respiratory infection
- Urticaria
Less Frequent
- COVId-19
- Headache disorder
- Leukopenia
- Urinary tract infection
Rare or Very Rare
- Acneiform eruption
- Allergic conjunctivitis
- Basal cell carcinoma of skin
- Bruising
- Contact dermatitis
- Dyschromia
- Fever
- Flu-like symptoms
- Gastritis
- Gastroenteritis
- Hordeolum
- Hypertension
- Insomnia
- Nasal congestion
- Otitis externa
- Squamous cell carcinoma of skin
- Symptoms of anxiety
- Vomiting
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Atopic dermatitis | ||
| L20 | ICD10CM | Atopic dermatitis |
| L20.0 | ICD10CM | Besnier's prurigo |
| L20.8 | ICD10CM | Other atopic dermatitis |
| L20.81 | ICD10CM | Atopic neurodermatitis |
| L20.82 | ICD10CM | Flexural eczema |
| L20.84 | ICD10CM | Intrinsic (allergic) eczema |
| L20.89 | ICD10CM | Other atopic dermatitis |
| L20.9 | ICD10CM | Atopic dermatitis, unspecified |
| Vitiligo | ||
| H02.73 | ICD10CM | Vitiligo of eyelid and periocular area |
| H02.731 | ICD10CM | Vitiligo of right upper eyelid and periocular area |
| H02.732 | ICD10CM | Vitiligo of right lower eyelid and periocular area |
| H02.733 | ICD10CM | Vitiligo of right eye, unspecified eyelid and periocular area |
| H02.734 | ICD10CM | Vitiligo of left upper eyelid and periocular area |
| H02.735 | ICD10CM | Vitiligo of left lower eyelid and periocular area |
| H02.736 | ICD10CM | Vitiligo of left eye, unspecified eyelid and periocular area |
| H02.739 | ICD10CM | Vitiligo of unspecified eye, unspecified eyelid and periocular area |
| L80 | ICD10CM | Vitiligo |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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