Ethyol (amifostine crystalline)
Thiol-Type Renal/Tissue Protectants Intravenous Vial (Ea)
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: Amifostine is used to decrease the risk of kidney problems caused by treatment with a certain anti-cancer drug (cisplatin). It is also used to help prevent a certain side effect (dry mouth) caused by radiation treatment for head and neck cancer. Amifostine is thought to work by preventing certain chemicals from damaging healthy cells.
It may also help repair cells damaged by cisplatin or radiation treatment.
Generic name: amifostine crystalline
Pronunciation: (A-mi-FOS-teen)
Drug class: Thiol-Type Renal/Tissue Protectants
Therapeutic class: Antineoplastics
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Ethyol
Indications
The following indications are listed for Ethyol:
- Prevention Of Cancer Chemotherapy-Induced Renal Impairment
- Prevention Of Xerostomia Secondary To Radiation Therapy
Also known as: Impaired Renal Function Due To Chemotherapy, Renal Function Impairment Due To Chemotherapy, Renal Insufficiency Due To Chemotherapy.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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- Dehydration
- Hypotension
- Hypovolemia
- Lactation
- Hypocalcemia
- Vomiting
- Cardiac arrhythmia
- Cerebrovascular accident
- Chronic heart failure
- Myocardial ischemia
- Transient cerebral ischemia
Adverse reactions
There is no enhanced messaging for this drug.
More Frequent
- Hypotension
Rare or Very Rare
- Acute myocardial infarction
- Acute respiratory failure
- Anaphylaxis
- Apnea
- Atrial fibrillation
- Atrial flutter
- Bradycardia
- Cardiac arrest
- DRESS syndrome
- Dyspnea
- Erythema multiforme
- Exfoliative dermatitis
- Extrasystoles
- Hypertension
- Hypocalcemia
- Hypoxia
- Laryngeal edema
- Palmar rash
- Renal failure
- Seizure disorder
- Stevens-johnson syndrome
- Supraventricular tachycardia
- Tachycardia
- Toxic epidermal necrolysis
- Urticaria
More Frequent
- Nausea
- Vomiting
Rare or Very Rare
- Allergic dermatitis
- Blurred vision
- Chest pain
- Chills
- Diplopia
- Dizziness
- Drowsy
- Fever
- Flushing
- Hiccups
- Injection site sequelae
- Malaise
- Pruritus of skin
- Skin rash
- Sneezing
- Syncope
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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