Opium Tincture (opium tincture)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Opium, a naturally occurring opiate agonist, is an antiperistaltic antidiarrhea agent.

Opium preparations are used for their constipating effect in the symptomatic treatment of diarrhea. Although paregoric is widely used, the less complex and more potent opium tincture is preferred by some clinicians. Opium preparations should not be used in patients with diarrhea caused by poisoning until the toxic material is eliminated from the GI tract by gastric lavage or cathartics.

Opium preparations are frequently used in combination with kaolin and pectin, which have adsorbent and protective properties. Bismuth salts are also common ingredients in commercially available opium preparation combination products, presumably for their adsorbent and protective effects.

Generic name: opium tincture
Pronunciation: (OH-pee-um)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

No indications are available for this drug.

Dosing

The usual adult dosage of paregoric for the treatment of diarrhea is 5-10 mL 1-4 times daily. The usual pediatric dosage of paregoric is 0.25-0.5 mL/kg 1-4 times daily.

The usual adult dosage of opium tincture for the treatment of diarrhea is 0.6 mL 4 times daily and may range from 0.3-1 mL 4 times daily. Single doses should not exceed 1 mL and dosage should not exceed 6 mL daily. Opium tincture contains 25 times more morphine than does paregoric and should never be confused with the latter preparation.

Drug interactions

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Contraindications

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Adverse reactions

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Precautions

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ICD codes

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Last reviewed · Source: First Databank (FDB) drug data