Clear Eyes Itchy Eye Relief (naphazoline HCl/zinc sulfate/glycerin)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Naphazoline hydrochloride, an imidazoline-derivative sympathomimetic amine, is a vasoconstrictor.
Zinc sulfate is an astringent and weak antiseptic.
USES: Naphazoline is a decongestant used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses). It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion. Some brands of naphazoline eye drops also contain other ingredients.
Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation. Zinc sulfate, an astringent, helps reduce redness and irritation.
Generic name: naphazoline HCl/zinc sulfate/glycerin
Pronunciation: (nah-FAZZ-oh-leen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
The following indications are listed for Clear Eyes Itchy Eye Relief:
- Dry Eye
- Ocular Irritation
- Ocular Redness
Also known as: Eye Dryness, Eye Redness, Ocular Erythema, Ophthalmic Irritation, Xerophthalmia.
Dosing
For relief of minor eye irritation, 1 or 2 drops of a zinc sulfate ophthalmic solution in combination with a vasoconstrictor are instilled onto the eye 2-4 times daily. Ophthalmic solutions containing zinc sulfate should generally not be used for self-medication for more than 3 days. Patients should be instructed to contact a physician if relief is not obtained within 3 days, or if redness or irritation persists or increases, since these may be signs or symptoms of a serious ocular condition.
Ophthalmic solutions of naphazoline hydrochloride are applied topically to the conjunctiva. Care must be taken to avoid contamination of the dropper tip. Some manufacturers recommend that contact lenses be removed before administration of ophthalmic solutions containing naphazoline.
Naphazoline hydrochloride nasal solutions are applied topically to the nasal mucosa. To minimize the risk of spreading infection, containers should not be used by more than one person.
Zinc sulfate ophthalmic solution is applied topically to the eye in the form of a solution. To prevent contamination of the solution, patients should be instructed to avoid contacting the tip of the container to any other surface and to tightly close the container after use.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Concurrent use of maprotiline or tricyclic antidepressants with naphazoline hydrochloride may potentiate the pressor effects of naphazoline.
Patients being treated with monoamine oxidase (MAO) inhibitors may experience a severe hypertensive reaction if administered with a sympathomimetic drug. Although this reaction has not specifically been reported with naphazoline, the possibility of such an interaction should be considered.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal studies have not been conducted with naphazoline hydrochloride, and it is not known whether the drug can cause fetal harm when administered to a pregnant woman. Therefore, naphazoline hydrochloride should be used during pregnancy only when clearly needed.
It is not known whether naphazoline hydrochloride is distributed into milk. Because many drugs are distributed into milk, caution should be exercised when this drug is administered to a breast-feeding woman.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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