Miconazole-Zinc Oxide-Petroltm (miconazole nitrate/zinc oxide/petrolatum,white)
Topical Antifungals Topical Ointment (GRAM)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Miconazole nitrate, an imidazole derivative, a synthetic azole antifungal agents.
USES: This product is used by children to treat diaper rash with a yeast infection, along with proper cleaning of the diaper area and frequent diaper changes. Miconazole is an azole antifungal that works by preventing the growth of fungus. Zinc oxide and petrolatum work by forming a barrier on the skin to protect it from moisture and irritation.
This product should not be used long-term or to prevent diaper rash.
Generic name: miconazole nitrate/zinc oxide/petrolatum,white
Pronunciation: (mye-KON-a-zole/zink-OX-ide/peh-truh-LAY-tum)
Drug class: Topical Antifungals
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Miconazole-Zinc Oxide-Petroltm
Indications
The following indications are listed for Miconazole-Zinc Oxide-Petroltm:
- Diaper Rash
Also known as: Diaper Dermatitis.
Dosing
No dosing information is available for this tab.
Miconazole nitrate is administered topically as a cream, powder, or aerosol powder or tincture, or intravaginally as a vaginal cream or suppository. Miconazole powder or aerosol powder are not recommended for use on the scalp or nails.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Blistering skin
- Skin rash
Rare or Very Rare
- Dermatitis due to topical drug
- Erythema
- Paresthesia
- Skin irritation
Precautions
No enhanced messaging available.
No enhanced messaging available.
Because small amounts of miconazole nitrate are absorbed from the vagina, the manufacturer states that the vaginal preparations should not be used in the first trimester of pregnancy unless the drug is considered essential to the welfare of the patient. For self-medication, miconazole nitrate vaginal suppositories or vaginal cream should not be used in pregnant women unless otherwise instructed by a physician. Follow-up reports from clinical studies during which miconazole vaginal preparations were used for up to 14 days in pregnant women have revealed no adverse effects or complications attributable to therapy with the drug in infants born to these women. Prolonged gestation has occurred in rats, but not in rabbits, receiving oral miconazole nitrate. In addition, fetotoxicity and embryotoxicity have occurred in rats and rabbits and dystocia in rats in reproduction studies using oral miconazole nitrate dosages of 80 mg/kg and higher; these effects were not observed in rats following intravaginal administration of the drug.
It is not known whether miconazole nitrate is distributed into milk. Miconazole nitrate should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Diaper rash | ||
| L22 | ICD10CM | Diaper dermatitis |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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