Terbinafine (terbinafine HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Terbinafine hydrochloride is a synthetic allylamine antifungal agent.
Terbinafine hydrochloride is a synthetic allylamine antifungal agent. Terbinafine is structurally and pharmacologically related to naftifine.
Terbinafine is commercially available for oral administration as tablets or film-coated granules containing terbinafine hydrochloride. The tablets should be stored at less than 25degreesC in a tight container and should be protected from light. The oral granules should be stored at 25degreesC, but may be exposed to temperatures ranging from 15-30degreesC.
USES: Terbinafine is used to treat certain types of fungal infections (for example, of the fingernail or toenail). It works by stopping the growth of fungus. This medication belongs to a class of drugs known as antifungals.
Generic name: terbinafine HCl
Pronunciation: (ter-BIN-uh-feen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Terbinafine
Indications
The following indications are listed for Terbinafine:
- Fingernail Onychomycosis
- Onychomycosis Due To Dermatophyte
- Toenail Onychomycosis
Also known as: Dermatophytosis Of The Nails, Onychomycosis, Onychomycosis Of Fingernail, Onychomycosis Of Toenail, Tinea Unguium, Tinea Unguium Of Fingernail, Tinea Unguium Of Toenail.
Dosing
Dosage of terbinafine hydrochloride is expressed in terms of terbinafine.
Terbinafine hydrochloride tablets are used in adults; terbinafine hydrochloride oral granules are used in adults or children 4 years of age or older.
Terbinafine hydrochloride is administered orally.
Terbinafine hydrochloride oral granules should be taken with food. The contents of the single-dose packet should be sprinkled on a spoonful of pudding or other soft, nonacidic food (e.g., mashed potatoes); applesauce or fruit-based food should not be used. The entire spoonful should be swallowed (without chewing). If the indicated dosage requires 2 packets for each dose, the contents of both packets may be sprinkled on a single spoonful of nonacidic food or the contents of the packets may be sprinkled on 2 spoonfuls of nonacidic food.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
Hypersensitivity to terbinafine or any ingredient in the formulation.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
The most frequent adverse effects of oral terbinafine are GI effects (diarrhea, dyspepsia, nausea, vomiting, abdominal pain, taste disturbances), headache, fever, upper respiratory tract infection or symptoms (cough, nasopharyngitis, nasal congestion, pharyngolaryngeal pain, influenza), liver test abnormalities, and dermatologic effects (rash, urticaria, pruritus).
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
Safety and efficacy of terbinafine tablets not established in children younger than 18 years of age.
Safety and efficacy of terbinafine oral granules not established in children younger than 4 years of age.
Category B. (See Users Guide.)
The manufacturer recommends that use of oral terbinafine be postponed until after pregnancy is completed.
Distributed into milk. Use not recommended.
Terbinafine oral granules have not been studied in geriatric patients.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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