Prednicarbate (prednicarbate)
Topical Corticosteroids Topical Cream (Gram)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Prednicarbate is a synthetic corticosteroid.
Prednicarbate is a synthetic, nonhalogenated corticosteroid. Prednicarbate is a 17,21-diester (17-ethylcarbonate, 21-propionate) derivative of prednisolone.
SumMon(R) (see Users Guide). For additional information on this drug until a more detailed monograph is developed and published, the manufacturer's labeling should be consulted. It is essential that the labeling be consulted for detailed information on the usual cautions, precautions, and contraindications.
Prednicarbate shares the actions of other topical corticosteroids and is used for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Generic name: prednicarbate
Pronunciation: (PRED-ni-KAR-bate)
Drug class: Topical Corticosteroids
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Prednicarbate
Indications
The following indications are listed for Prednicarbate:
- Allergic Dermatitis
- Atopic Dermatitis
- Contact Dermatitis
- Discoid Lupus Erythematosus
- Genital Organ Pruritus
- Granuloma Annulare
- Lichen Simplex Chronicus
- Plaque Psoriasis
- Pruritus Ani
- Pruritus Of Skin
- Pyoderma Gangrenosum
- Scalp Psoriasis
- Seborrheic Dermatitis
- Skin Inflammation
Also known as: Atopic Eczema, Circumscribed Neurodermatitis, Dermatitis, Dermatitis Seborrheica, Dermatitis Venenata, Disseminated Neurodermatitis, Dyssebacea, Dyssebacia, Genital Pruritus, Itchy Skin Eruption, Lichen Annularis, Pruritic Dermatitis, Seborrhea Corporis, Seborrheic Eczema, Unna's Disease, Vidal's Disease.
Dosing
The manufacturer states that safety and efficacy of prednicarbate cream in children younger than 1 year of age and of prednicarbate ointment in children younger than 10 years of age have not been established. Therefore, use of the drug in these children is not recommended.
Topical prednicarbate cream or ointment is applied sparingly in a thin film and rubbed gently into the affected area twice daily. Occlusive dressings may be used for severe or resistant dermatoses, but the risk of adverse local and systemic effects also increases with occlusion.
The manufacturer states that topical prednicarbate cream may be used with caution in children 1 year of age or older; however, safety and efficacy of long-term (i.e., longer than 3 weeks) use of topical prednicarbate cream in these children have not been established. In addition, parents or guardians of children should be advised that prednicarbate cream is not recommended for use in the treatment of diaper dermatitis since diapers or plastic pants may act as occlusive dressings.
No dosing information is available for this tab.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Prednicarbate 0.1% Cream | Maintenance | Apply a thin layer to the affected area(s) by topical route 2 times per day. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Prednicarbate 0.1% Cream | Maintenance | Apply a thin layer to the affected area(s) by topical route 2 times per day. |
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
- Bacterial skin and skin structure infection
- Hypothalamic-pituitary insufficiency
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Skin atrophy
Rare or Very Rare
- Acneiform eruption
- Dermatitis due to topical drug
- Edema
- Folliculitis
- Paresthesia
- Pruritus of skin
- Skin and skin structure infection
- Skin hypopigmentation
- Skin rash
- Skin striae
- Telangiectasia
- Urticaria
Rare or Very Rare
- Hypercortisolism
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Allergic dermatitis | ||
| L20 | ICD10CM | Atopic dermatitis |
| L20.0 | ICD10CM | Besnier's prurigo |
| L20.8 | ICD10CM | Other atopic dermatitis |
| L20.81 | ICD10CM | Atopic neurodermatitis |
| L20.82 | ICD10CM | Flexural eczema |
| L20.83 | ICD10CM | Infantile (acute) (chronic) eczema |
| L20.84 | ICD10CM | Intrinsic (allergic) eczema |
| L20.89 | ICD10CM | Other atopic dermatitis |
| L20.9 | ICD10CM | Atopic dermatitis, unspecified |
| L23 | ICD10CM | Allergic contact dermatitis |
| L23.0 | ICD10CM | Allergic contact dermatitis due to metals |
| L23.1 | ICD10CM | Allergic contact dermatitis due to adhesives |
| L23.2 | ICD10CM | Allergic contact dermatitis due to cosmetics |
| L23.3 | ICD10CM | Allergic contact dermatitis due to drugs in contact with skin |
| L23.4 | ICD10CM | Allergic contact dermatitis due to dyes |
| L23.5 | ICD10CM | Allergic contact dermatitis due to other chemical products |
| L23.6 | ICD10CM | Allergic contact dermatitis due to food in contact with the skin |
| L23.7 | ICD10CM | Allergic contact dermatitis due to plants, except food |
| L23.8 | ICD10CM | Allergic contact dermatitis due to other agents |
| L23.81 | ICD10CM | Allergic contact dermatitis due to animal (cat) (dog) dander |
| L23.89 | ICD10CM | Allergic contact dermatitis due to other agents |
| L23.9 | ICD10CM | Allergic contact dermatitis, unspecified cause |
| Atopic dermatitis | ||
| L20 | ICD10CM | Atopic dermatitis |
| L20.0 | ICD10CM | Besnier's prurigo |
| L20.8 | ICD10CM | Other atopic dermatitis |
| L20.81 | ICD10CM | Atopic neurodermatitis |
| L20.82 | ICD10CM | Flexural eczema |
| L20.84 | ICD10CM | Intrinsic (allergic) eczema |
| L20.89 | ICD10CM | Other atopic dermatitis |
| L20.9 | ICD10CM | Atopic dermatitis, unspecified |
| Contact dermatitis | ||
| L23 | ICD10CM | Allergic contact dermatitis |
| L23.0 | ICD10CM | Allergic contact dermatitis due to metals |
| L23.1 | ICD10CM | Allergic contact dermatitis due to adhesives |
| L23.2 | ICD10CM | Allergic contact dermatitis due to cosmetics |
| L23.3 | ICD10CM | Allergic contact dermatitis due to drugs in contact with skin |
| L23.4 | ICD10CM | Allergic contact dermatitis due to dyes |
| L23.5 | ICD10CM | Allergic contact dermatitis due to other chemical products |
| L23.6 | ICD10CM | Allergic contact dermatitis due to food in contact with the skin |
| L23.7 | ICD10CM | Allergic contact dermatitis due to plants, except food |
| L23.8 | ICD10CM | Allergic contact dermatitis due to other agents |
| L23.81 | ICD10CM | Allergic contact dermatitis due to animal (cat) (dog) dander |
| L23.89 | ICD10CM | Allergic contact dermatitis due to other agents |
| L23.9 | ICD10CM | Allergic contact dermatitis, unspecified cause |
| L24 | ICD10CM | Irritant contact dermatitis |
| L24.0 | ICD10CM | Irritant contact dermatitis due to detergents |
| L24.1 | ICD10CM | Irritant contact dermatitis due to oils and greases |
| L24.2 | ICD10CM | Irritant contact dermatitis due to solvents |
| L24.3 | ICD10CM | Irritant contact dermatitis due to cosmetics |
| L24.4 | ICD10CM | Irritant contact dermatitis due to drugs in contact with skin |
| L24.5 | ICD10CM | Irritant contact dermatitis due to other chemical products |
| L24.6 | ICD10CM | Irritant contact dermatitis due to food in contact with skin |
| L24.7 | ICD10CM | Irritant contact dermatitis due to plants, except food |
| L24.8 | ICD10CM | Irritant contact dermatitis due to other agents |
| L24.81 | ICD10CM | Irritant contact dermatitis due to metals |
| L24.89 | ICD10CM | Irritant contact dermatitis due to other agents |
| L24.9 | ICD10CM | Irritant contact dermatitis, unspecified cause |
| L24.A0 | ICD10CM | Irritant contact dermatitis due to friction or contact with body fluids, unspecified |
| L24.A1 | ICD10CM | Irritant contact dermatitis due to saliva |
| L24.A2 | ICD10CM | Irritant contact dermatitis due to fecal, urinary or dual incontinence |
| L24.A9 | ICD10CM | Irritant contact dermatitis due friction or contact with other specified body fluids |
| L24.B | ICD10CM | Irritant contact dermatitis related to stoma or fistula |
| L24.B0 | ICD10CM | Irritant contact dermatitis related to unspecified stoma or fistula |
| L24.B1 | ICD10CM | Irritant contact dermatitis related to digestive stoma or fistula |
| L24.B2 | ICD10CM | Irritant contact dermatitis related to respiratory stoma or fistula |
| L24.B3 | ICD10CM | Irritant contact dermatitis related to fecal or urinary stoma or fistula |
| L25 | ICD10CM | Unspecified contact dermatitis |
| L25.0 | ICD10CM | Unspecified contact dermatitis due to cosmetics |
| L25.1 | ICD10CM | Unspecified contact dermatitis due to drugs in contact with skin |
| L25.2 | ICD10CM | Unspecified contact dermatitis due to dyes |
| L25.3 | ICD10CM | Unspecified contact dermatitis due to other chemical products |
| L25.4 | ICD10CM | Unspecified contact dermatitis due to food in contact with skin |
| L25.5 | ICD10CM | Unspecified contact dermatitis due to plants, except food |
| L25.8 | ICD10CM | Unspecified contact dermatitis due to other agents |
| L25.9 | ICD10CM | Unspecified contact dermatitis, unspecified cause |
| Discoid lupus erythematosus | ||
| H01.12 | ICD10CM | Discoid lupus erythematosus of eyelid |
| H01.121 | ICD10CM | Discoid lupus erythematosus of right upper eyelid |
| H01.122 | ICD10CM | Discoid lupus erythematosus of right lower eyelid |
| H01.123 | ICD10CM | Discoid lupus erythematosus of right eye, unspecified eyelid |
| H01.124 | ICD10CM | Discoid lupus erythematosus of left upper eyelid |
| H01.125 | ICD10CM | Discoid lupus erythematosus of left lower eyelid |
| H01.126 | ICD10CM | Discoid lupus erythematosus of left eye, unspecified eyelid |
| H01.129 | ICD10CM | Discoid lupus erythematosus of unspecified eye, unspecified eyelid |
| L93.0 | ICD10CM | Discoid lupus erythematosus |
| Genital organ pruritus | ||
| L29.2 | ICD10CM | Pruritus vulvae |
| L29.3 | ICD10CM | Anogenital pruritus, unspecified |
| Granuloma annulare | ||
| L92.0 | ICD10CM | Granuloma annulare |
| Lichen simplex chronicus | ||
| L28.0 | ICD10CM | Lichen simplex chronicus |
| Plaque psoriasis | ||
| L40.0 | ICD10CM | Psoriasis vulgaris |
| L40.9 | ICD10CM | Psoriasis, unspecified |
| Pruritus ani | ||
| L29.0 | ICD10CM | Pruritus ani |
| L29.3 | ICD10CM | Anogenital pruritus, unspecified |
| Pruritus of skin | ||
| L29.8 | ICD10CM | Other pruritus |
| L29.81 | ICD10CM | Cholestatic pruritus |
| L29.89 | ICD10CM | Other pruritus |
| L29.9 | ICD10CM | Pruritus, unspecified |
| Pyoderma gangrenosum | ||
| L88 | ICD10CM | Pyoderma gangrenosum |
| Scalp psoriasis | ||
| L40.0 | ICD10CM | Psoriasis vulgaris |
| L40.1 | ICD10CM | Generalized pustular psoriasis |
| L40.4 | ICD10CM | Guttate psoriasis |
| L40.8 | ICD10CM | Other psoriasis |
| L40.9 | ICD10CM | Psoriasis, unspecified |
| Seborrheic dermatitis | ||
| L21 | ICD10CM | Seborrheic dermatitis |
| L21.0 | ICD10CM | Seborrhea capitis |
| L21.1 | ICD10CM | Seborrheic infantile dermatitis |
| L21.8 | ICD10CM | Other seborrheic dermatitis |
| L21.9 | ICD10CM | Seborrheic dermatitis, unspecified |
| Skin inflammation | ||
| H01.81 | ICD10CM | Other specified inflammation of right upper eyelid |
| H01.82 | ICD10CM | Other specified inflammation of right lower eyelid |
| H01.83 | ICD10CM | Other specified inflammation of right eye, unspecified eyelid |
| H01.84 | ICD10CM | Other specified inflammation of left upper eyelid |
| H01.85 | ICD10CM | Other specified inflammation of left lower eyelid |
| H01.86 | ICD10CM | Other specified inflammation of left eye, unspecified eyelid |
| H01.89 | ICD10CM | Other specified inflammation of unspecified eye, unspecified eyelid |
| H01.8A | ICD10CM | Other specified inflammation of right eye, upper and lower eyelids |
| H01.8B | ICD10CM | Other specified inflammation of left eye, upper and lower eyelids |
| L20 | ICD10CM | Atopic dermatitis |
| L20.8 | ICD10CM | Other atopic dermatitis |
| L20.89 | ICD10CM | Other atopic dermatitis |
| L20.9 | ICD10CM | Atopic dermatitis, unspecified |
| L21 | ICD10CM | Seborrheic dermatitis |
| L21.8 | ICD10CM | Other seborrheic dermatitis |
| L21.9 | ICD10CM | Seborrheic dermatitis, unspecified |
| L25 | ICD10CM | Unspecified contact dermatitis |
| L30.8 | ICD10CM | Other specified dermatitis |
| L30.9 | ICD10CM | Dermatitis, unspecified |
| L40 | ICD10CM | Psoriasis |
| L40.1 | ICD10CM | Generalized pustular psoriasis |
| L40.8 | ICD10CM | Other psoriasis |
| L40.9 | ICD10CM | Psoriasis, unspecified |
| R21 | ICD10CM | Rash and other nonspecific skin eruption |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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