Belladonna-Opium (opium/belladonna alkaloids)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Opium, the air-dried milky exudate obtained by incising the unripe capsules of Papaver somniferum Linne or its variety album De Candolle, Opium contains several alkaloids, including not less than 9.5% anhydrous morphine and small amounts of codeine and papaverine.
Combination preparations containing powdered opium and belladonna extract in rectal suppository form are used for the relief of moderate to severe pain associated with ureteral spasm that is not responsive to non-opiate analgesics or for other conditions in which the analgesic, sedative, and antispasmodic effects of the combination may be useful such as when pain and smooth-muscle spasm are present concurrently.
Generic name: opium/belladonna alkaloids
Pronunciation: (OH-pee-um/BEL-a-DON-a)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Belladonna-Opium
Indications
No indications are available for this drug.
Dosing
Opium preparations should be given at the lowest effective dosage and for the shortest duration of therapy consistent with the treatment goals of the patient. Reduced dosage is indicated in debilitated patients and in very young or very old patients. If concomitant therapy with other CNS depressants is required, the lowest effective dosages and shortest possible duration of concomitant therapy should be used.
The usual adult rectal dosage of combination preparations containing powdered opium is one suppository once or twice daily, or as directed by a physician; prior to rectal insertion, the finger and suppository should be moistened.
Combination preparations containing powdered opium in suppository form are administered rectally.
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No dosing information is available for this tab.
Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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