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Gentamicin Sulfate (gentamicin sulfate)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Gentamicin is an aminoglycoside antibiotic.

Gentamicin is used topically in the treatment of superficial infections of the skin caused by susceptible bacteria. However, substantial evidence of effectiveness is lacking and some experts question the use of topical antibiotics in general. Minor skin infections and wounds usually heal without treatment, and systemic anti-infective therapy is required for the treatment of serious or extensive skin infections.

In addition, indiscriminate use of topical gentamicin may result in the emergence of organisms resistant to the drug and other aminoglycosides.

Generic name: gentamicin sulfate
Pronunciation: (JEN-ta-MYE-sin)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

The following indications are listed for Gentamicin Sulfate:

  • Bacterial Skin And Skin Structure Infection
  • Folliculitis
  • Furunculosis
  • Paronychia

Also known as: Bacterial Skin Infection, Furuncle, Onychia Lateralis, Onychia Periungualis, Perionychia, Perionyxis.

Dosing

Gentamicin sulfate is applied topically to the skin in the form of a cream or ointment containing 0.1% gentamicin. Because the ointment helps retain moisture, it has been used in the treatment of infections on dry, eczematous, or psoriatic skin. The cream is usually used for the treatment of wet, oozing primary infections and greasy secondary infections; the cream is also used if a water-washable preparation is desired.

A small amount of gentamicin cream or ointment should be applied gently to the cleansed affected area 3-4 times daily. The area may be covered with a sterile gauze dressing; infected stasis ulcers may be covered with gelatin packing. In the topical treatment of impetigo, crusts should be removed from the lesions to permit contact between the antibiotic and the infection. Care should be taken to avoid further contamination of the infected skin.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

There is no enhanced messaging for this drug.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data