Gel-Flow (thrombin (bovine)/gelatin sponge,absorbable)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Thrombin (bovine), a protein produced via limited proteolysis of bovine prothrombin, is a topical hemostatic agent.
Thrombin (bovine) is used topically as an aid in achieving hemostasis at accessible sites of oozing blood and minor bleeding from capillaries and small venules. Thrombin (bovine) alone does not control arterial bleeding. In various types of surgery, thrombin (bovine) solutions may be used in conjunction with an absorbable gelatin sponge to establish hemostasis.
Generic name: thrombin (bovine)/gelatin sponge,absorbable
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
The following indications are listed for Gel-Flow:
- Surgical Hemostasis Adjunct
Dosing
The concentration of thrombin (bovine) solutions used depends on the severity of bleeding. Thrombin (bovine) is reconstituted to the desired concentration using 0.9% sodium chloride; solutions should be used promptly following removal from the container. (See Chemistry and Stability: Stability.) For general use such as in plastic surgery, dental extractions, or skin grafting, thrombin (bovine) solutions containing approximately 100 units/mL are usually used. Where bleeding is profuse (e.g., from cut surfaces of the liver or spleen), concentrations as high as 1000 units/mL may be required.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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Animal reproduction studies have not been performed with topical thrombin (bovine). It is also not known whether topical thrombin (bovine) can cause fetal harm when administered to pregnant women. Topical thrombin (bovine) should be used during pregnancy only when clearly needed.
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No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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