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Keflex (cephalexin)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Cephalexin is a semisynthetic, first generation cephalosporin antibiotic.

USES: This medication is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

Generic name: cephalexin
Pronunciation: (SEF-a-LEX-in)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Keflex

Intelligence content is not available yet.

Indications

The following indications are listed for Keflex:

  • Acute Bacterial Otitis Media
  • Bacterial Urinary Tract Infection
  • Bone Infection
  • E. Coli Prostatitis
  • E. Coli Urinary Tract Infection
  • Haemophilus Influenzae Acute Otitis Media
  • Infectious Disorder Of Joint
  • Klebsiella Prostatitis
  • Klebsiella Urinary Tract Infection
  • Moraxella Catarrhalis Acute Otitis Media
  • Pharyngitis Due To Streptococcus Pyogenes
  • Proteus Prostatitis
  • Proteus Urinary Tract Infection
  • Skin And Skin Structure Infection
  • Skin And Skin Structure Streptococcus Pyogenes Infection
  • Staphylococcus Acute Otitis Media
  • Staphylococcus Aureus Osteomyelitis
  • Staphylococcus Aureus Skin And Skin Structure Infection
  • Streptococcal Pneumonia
  • Streptococcus Acute Otitis Media
  • Streptococcus Osteomyelitis
  • Tonsillitis Due To Streptococcus Pyogenes

Also known as: Acute Otitis Media Due To H. Flu, Acute Otitis Media Due To Haemophilus Influenzae, Acute Otitis Media Due To Hemophilus Influenzae, Acute Otitis Media Due To Influenza Bacillus, Acute Otitis Media Due To Moraxella Catarrhalis, Acute Otitis Media Due To Pfeiffer's Bacillus, Acute Otitis Media Due To Staphylococcus Species, Acute Otitis Media Due To Streptococcus Species, Bacterial Infection Of Prostate Due To Proteus Species, Bacterial Infection Of The Prostate Due To E. Coli, Bacterial Infection Of The Prostate Due To Klebsiella, Bacterial Otitis Media, E. Coli Uti, Epidemic Sore Throat, Infection Of Skin And/Or Subcutaneous Tissue, Joint Infection, Klebsiella Uti, Osteomyelitis Due To Staphylococcus Aureus, Osteomyelitis Due To Staphylococcus Pyogenes Aureus, Osteomyelitis Due To Streptococcus, Pharyngitis Due To Group A Beta-Hemolytic Streptococci, Pharyngitis Due To Streptococcus Epidemicus, Pneumonia Due To Streptococcus Species, Pneumonia Due To Streptococcus Spp., Prostatitis Due To E. Coli, Prostatitis Due To Escherichia Coli, Prostatitis Due To Klebsiella Species, Prostatitis Due To Proteus Species, Pyogenic Bone Infection Due To Staphylococcus Aureus, Pyogenic Bone Infection Due To Streptococcus, Septic Sore Throat, Skin & Skin Soft Tissue Streptococcus Pyogenes Infection, Skin And Skin Soft Tissue Staphylococcus Aureus Infection, Skin And Soft Tissue Skin Infection, Staphylococcal Acute Otitis Media, Streptococcal Pharyngitis, Streptococcus Pyogenes Tonsillitis, Urinary Tract Infection Due To Escherichia Coli, Urinary Tract Infection Due To Klebsiella Species, Urinary Tract Infection Due To Proteus Species, Uti Due To Proteus Species.

Dosing

Cephalexin is commercially available as the monohydrate; dosage is expressed in terms of cephalexin.

The manufacturers state that cephalexin should be used with caution in patients with markedly impaired renal function, and close clinical observation and laboratory studies are recommended in such patients because safe dosage may be lower than usual dosages.

Some clinicians state that modification of the usual dosage does not appear to be necessary in patients with creatinine clearances greater than 40 mL/minute. These clinicians suggest that the usual adult dosage be used for the initial dose. Then, for subsequent doses, adults with creatinine clearances of 11-40 mL/minute should receive 500 mg every 8-12 hours, those with creatinine clearances of 5-10 mL/minute should receive 250 mg every 12 hours, and those with creatinine clearances less than 5 mL/minute should receive 250 mg every 12-24 hours.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

There is no enhanced messaging for this drug.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data