Ketoconazole (ketoconazole)
Topical Antifungals Topical Cream (Gram); Topical Shampoo
Last reviewed · Source: First Databank (FDB) drug data
Overview
Ketoconazole, a synthetic azole antifungal agent, is an imidazole derivative.
USES: Ketoconazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and certain kinds of dandruff. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Ketoconazole is an azole antifungal that works by preventing the growth of fungus.
Generic name: ketoconazole
Pronunciation: (kee-toe-CON-uh-zole)
Drug class: Topical Antifungals
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Ketoconazole
Indications
The following indications are listed for Ketoconazole:
- Cutaneous Candidiasis
- Fungal Infection Of Skin
- Seborrheic Dermatitis
- Tinea Corporis
- Tinea Cruris
- Tinea Pedis
- Tinea Versicolor
Also known as: Corporeal Ringworm, Cutaneous Candidosis, Cutaneous Moniliasis, Dermatitis Seborrheica, Dermatomycosis, Dermatomycosis Pedis, Dhobie Itch, Dyssebacea, Dyssebacia, Eczema Marginatum, Fungal Dermatologic Infection, Fungal Skin Infection, Jock Itch, Pityriasis Versicolor, Seborrhea Corporis, Seborrheic Eczema, Tinea Circinata, Tinea Furfuracea, Tinea Glabrosa, Tinea Inguinalis, Tinea Of The Foot, Unna's Disease.
Dosing
No dosing information is available for this tab.
Ketoconazole is applied topically to the skin as a 2% cream, foam, gel, or shampoo.
Ketoconazole is applied topically to the hair and scalp as a 1% shampoo. The drug also has been applied topically to hair+ and scalp+ as a 2% shampoo.
Ketoconazole topical cream, foam, gel, and shampoo are for external use only. These topical preparations should not be applied to the eyes and should not be administered orally or intravaginally.
If contact with eyes, mouth, or vagina occurs, the exposed areas should be rinsed thoroughly with water.
Fire, flame, and/or smoking should be avoided during and immediately after application of ketoconazole 2% foam or gel. (See Cautions: Precautions and Contraindications.)
| Drug label | Dosing type | Instructions |
|---|---|---|
| Ketoconazole 2% Cream | Maintenance | Apply to the affected area(s) by topical route once daily. |
| Ketoconazole 2% Shampoo | Maintenance | Apply to the affected area(s), lather, leave in place for 5 minutes, and then rinse off with water by topical route once daily. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Ketoconazole 2% Cream | Maintenance | Apply to the affected area(s) by topical route once daily. |
| Ketoconazole 2% Shampoo | Maintenance | Apply to the affected area(s), lather, leave in place for 5 minutes, and then rinse off with water by topical route once daily. |
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Anaphylaxis
- Angioedema
More Frequent
- Pruritus of skin
- Skin inflammation
- Skin irritation
Rare or Very Rare
- Abnormal hair texture
- Alopecia
- Cheilitis
- Dermatitis due to topical drug
- Dry skin
- Erythema
- Hair discoloration
- Skin rash
- Stinging of skin
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Cutaneous candidiasis | ||
| B37.2 | ICD10CM | Candidiasis of skin and nail |
| Fungal infection of skin | ||
| B35 | ICD10CM | Dermatophytosis |
| B35.0 | ICD10CM | Tinea barbae and tinea capitis |
| B35.1 | ICD10CM | Tinea unguium |
| B35.2 | ICD10CM | Tinea manuum |
| B35.3 | ICD10CM | Tinea pedis |
| B35.4 | ICD10CM | Tinea corporis |
| B35.5 | ICD10CM | Tinea imbricata |
| B35.6 | ICD10CM | Tinea cruris |
| B35.8 | ICD10CM | Other dermatophytoses |
| B35.9 | ICD10CM | Dermatophytosis, unspecified |
| B36 | ICD10CM | Other superficial mycoses |
| B36.0 | ICD10CM | Pityriasis versicolor |
| B36.1 | ICD10CM | Tinea nigra |
| B36.2 | ICD10CM | White piedra |
| B36.3 | ICD10CM | Black piedra |
| B36.8 | ICD10CM | Other specified superficial mycoses |
| B36.9 | ICD10CM | Superficial mycosis, unspecified |
| B37.2 | ICD10CM | Candidiasis of skin and nail |
| B37.31 | ICD10CM | Acute candidiasis of vulva and vagina |
| B37.32 | ICD10CM | Chronic candidiasis of vulva and vagina |
| Seborrheic dermatitis | ||
| L21 | ICD10CM | Seborrheic dermatitis |
| L21.0 | ICD10CM | Seborrhea capitis |
| L21.1 | ICD10CM | Seborrheic infantile dermatitis |
| L21.8 | ICD10CM | Other seborrheic dermatitis |
| L21.9 | ICD10CM | Seborrheic dermatitis, unspecified |
| Tinea corporis | ||
| B35.4 | ICD10CM | Tinea corporis |
| Tinea cruris | ||
| B35.6 | ICD10CM | Tinea cruris |
| Tinea pedis | ||
| B35.3 | ICD10CM | Tinea pedis |
| Tinea versicolor | ||
| B36.0 | ICD10CM | Pityriasis versicolor |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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