Cyto B-1 (thiamine mononitrate (vit B1))
Vitamin B-1 Oral Powder (GRAM)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Thiamine is a water-soluble, B complex vitamin.
Generic name: thiamine mononitrate (vit B1)
Drug class: Vitamin B-1
Therapeutic class: Electrolyte Balance-Nutritional Products
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Cyto B-1
Indications
No indications are available for this drug.
Dosing
No dosing information is available for this tab.
Thiamine hydrochloride is usually administered orally. When oral administration is not feasible, when malabsorption is suspected, or in patients with Wernicke's encephalopathy syndrome or high-output heart failure secondary to beriberi, the drug may be administered IM or IV; most clinicians prefer IV administration of thiamine hydrochloride for the treatment of high-output heart failure.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Although the clinical importance is unknown, thiamine reportedly may enhance the effect of neuromuscular blocking agents.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
Moderate Interaction: Assess the risk to the patient and take action as needed.
Thiamine/Patiromer
SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed.
MECHANISM OF ACTION: Patiromer may bind to thiamine.(1)
CLINICAL EFFECTS: Concurrent use may result in decreased gastrointestinal absorption and loss of efficacy of thiamine.(1)
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: The US manufacturer of patiromer recommends administering patiromer at least 3 hours before or 3 hours after thiamine.(1)
DISCUSSION: An in vitro binding study found potentially clinically significant binding of thiamine by patiromer. It is recommended to take these drugs 3 hours apart.(1)
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
- Systemic mastocytosis
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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