Oxiconazole Nitrate (oxiconazole nitrate)
Topical Antifungals Topical Cream (Gram)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Oxiconazole nitrate, an imidazole derivative, is a synthetic azole antifungal agent.
USES: Oxiconazole is used to treat skin infections such as athlete's foot, jock itch and ringworm. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Oxiconazole is an azole antifungal that works by preventing the growth of fungus.
Generic name: oxiconazole nitrate
Pronunciation: (ox-ee-CON-uh-zole)
Drug class: Topical Antifungals
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Oxiconazole Nitrate
Indications
The following indications are listed for Oxiconazole Nitrate:
- Tinea Corporis
- Tinea Cruris
- Tinea Pedis
- Tinea Versicolor
Also known as: Corporeal Ringworm, Dermatomycosis Pedis, Dhobie Itch, Eczema Marginatum, Jock Itch, Pityriasis Versicolor, Tinea Circinata, Tinea Furfuracea, Tinea Glabrosa, Tinea Inguinalis, Tinea Of The Foot.
Dosing
Dosage and potency of oxiconazole nitrate are expressed in terms of oxiconazole.
Oxiconazole nitrate is applied topically to the skin as a 1% cream or a lotion.
The cream or lotion should not be applied to the eye and should not be administered intravaginally.
Oxiconazole lotion should be shaken well before using.
A sufficient amount of oxiconazole 1% topical cream or lotion should be applied to the affected areas of skin and rubbed in gently.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Oxiconazole Nitrate 1% Cream | Maintenance | Apply to the affected and surrounding areas of skin by topical route once daily. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Oxiconazole Nitrate 1% Cream | Maintenance | Apply to the affected and surrounding areas of skin by topical route once daily. |
Drug interactions
Since only low amounts of oxiconazole nitrate are absorbed following topical application to skin, drug interactions are unlikely in patients receiving usual topical dosage of the drug. No formal drug interaction studies have been performed to date.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Hypersensitivity drug reaction
Less Frequent
- Erythema
- Pruritus of skin
- Skin irritation
- Stinging of skin
Precautions
No enhanced messaging available.
No enhanced messaging available.
Reproduction studies in rabbits, rats, and mice using oxiconazole dosages of up to 100, 150, and 200 mg/kg daily, respectively, have not revealed evidence of harm to the fetus. There are no adequate and controlled studies to date using topical oxiconazole nitrate in pregnant women, and the drug should be used during pregnancy only when clearly needed.
Since oxiconazole is distributed into milk, the manufacturer recommends that the drug be used topically with caution in nursing women.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Tinea corporis | ||
| B35.4 | ICD10CM | Tinea corporis |
| Tinea cruris | ||
| B35.6 | ICD10CM | Tinea cruris |
| Tinea pedis | ||
| B35.3 | ICD10CM | Tinea pedis |
| Tinea versicolor | ||
| B36.0 | ICD10CM | Pityriasis versicolor |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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