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Dermatop (prednicarbate)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Prednicarbate is a synthetic corticosteroid.

Prednicarbate is a synthetic, nonhalogenated corticosteroid. Prednicarbate is a 17,21-diester (17-ethylcarbonate, 21-propionate) derivative of prednisolone.

SumMon(R) (see Users Guide). For additional information on this drug until a more detailed monograph is developed and published, the manufacturer's labeling should be consulted. It is essential that the labeling be consulted for detailed information on the usual cautions, precautions, and contraindications.

Prednicarbate shares the actions of other topical corticosteroids and is used for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Generic name: prednicarbate
Pronunciation: (PRED-ni-KAR-bate)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

The following indications are listed for Dermatop:

  • Allergic Dermatitis
  • Atopic Dermatitis
  • Contact Dermatitis
  • Discoid Lupus Erythematosus
  • Genital Organ Pruritus
  • Granuloma Annulare
  • Lichen Simplex Chronicus
  • Plaque Psoriasis
  • Pruritus Ani
  • Pruritus Of Skin
  • Pyoderma Gangrenosum
  • Scalp Psoriasis
  • Seborrheic Dermatitis
  • Skin Inflammation

Also known as: Atopic Eczema, Circumscribed Neurodermatitis, Dermatitis, Dermatitis Seborrheica, Dermatitis Venenata, Disseminated Neurodermatitis, Dyssebacea, Dyssebacia, Genital Pruritus, Itchy Skin Eruption, Lichen Annularis, Pruritic Dermatitis, Seborrhea Corporis, Seborrheic Eczema, Unna's Disease, Vidal's Disease.

Dosing

The manufacturer states that safety and efficacy of prednicarbate cream in children younger than 1 year of age and of prednicarbate ointment in children younger than 10 years of age have not been established. Therefore, use of the drug in these children is not recommended.

Topical prednicarbate cream or ointment is applied sparingly in a thin film and rubbed gently into the affected area twice daily. Occlusive dressings may be used for severe or resistant dermatoses, but the risk of adverse local and systemic effects also increases with occlusion.

The manufacturer states that topical prednicarbate cream may be used with caution in children 1 year of age or older; however, safety and efficacy of long-term (i.e., longer than 3 weeks) use of topical prednicarbate cream in these children have not been established. In addition, parents or guardians of children should be advised that prednicarbate cream is not recommended for use in the treatment of diaper dermatitis since diapers or plastic pants may act as occlusive dressings.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

There is no enhanced messaging for this drug.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data