Eye Allergy Relief (naphazoline HCl/pheniramine maleate)
Ophthalmic Decongestants Ophthalmic (EYE) Drops
Last reviewed · Source: First Databank (FDB) drug data
Overview
Naphazoline hydrochloride, an imidazoline-derivative sympathomimetic amine, is a vasoconstrictor.
USES: This medication is used to temporarily relieve eye redness, puffiness, itching, and watering that commonly occur with allergies. Naphazoline is a decongestant. It belongs to a class of drugs known as sympathomimetic amines.
It works by temporarily narrowing the blood vessels in the eye. Pheniramine is an antihistamine. It works by blocking certain natural substances (histamines) that cause allergic symptoms.
Do not use this medication to treat redness and irritation from wearing contact lenses.
Generic name: naphazoline HCl/pheniramine maleate
Pronunciation: (naf-AZ-oh-leen/fen-IR-a-meen)
Drug class: Ophthalmic Decongestants
Therapeutic class: Ophthalmic Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Eye Allergy Relief
Indications
The following indications are listed for Eye Allergy Relief:
- Ocular Itching
- Ocular Redness
Also known as: Eye Redness, Ocular Erythema, Ocular Pruritus.
Dosing
No dosing information is available for this tab.
Ophthalmic solutions of naphazoline hydrochloride are applied topically to the conjunctiva. Care must be taken to avoid contamination of the dropper tip. Some manufacturers recommend that contact lenses be removed before administration of ophthalmic solutions containing naphazoline.
Naphazoline hydrochloride nasal solutions are applied topically to the nasal mucosa. To minimize the risk of spreading infection, containers should not be used by more than one person.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Concurrent use of maprotiline or tricyclic antidepressants with naphazoline hydrochloride may potentiate the pressor effects of naphazoline.
Patients being treated with monoamine oxidase (MAO) inhibitors may experience a severe hypertensive reaction if administered with a sympathomimetic drug. Although this reaction has not specifically been reported with naphazoline, the possibility of such an interaction should be considered.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Angle-closure glaucoma
There are no severe contraindications for this drug.
- Diabetes mellitus
- Hypertension
- Hyperthyroidism
- Ocular infection
- Ocular injury
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Dizziness
- Hyperhidrosis
- Hypertension
- Ocular hypertension
- Punctate keratitis
Less Frequent
- Blurred vision
- Mydriasis
- Ocular irritation
Rare or Very Rare
- Drowsy
- General weakness
- Headache disorder
- Hyperglycemia
- Nausea
- Nervousness
- Photophobia
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal studies have not been conducted with naphazoline hydrochloride, and it is not known whether the drug can cause fetal harm when administered to a pregnant woman. Therefore, naphazoline hydrochloride should be used during pregnancy only when clearly needed.
It is not known whether naphazoline hydrochloride is distributed into milk. Because many drugs are distributed into milk, caution should be exercised when this drug is administered to a breast-feeding woman.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Ocular itching | ||
| H57.89 | ICD10CM | Other specified disorders of eye and adnexa |
| L29.8 | ICD10CM | Other pruritus |
| Ocular redness | ||
| H57.8 | ICD10CM | Other specified disorders of eye and adnexa |
| H57.89 | ICD10CM | Other specified disorders of eye and adnexa |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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