Diethylpropion (diethylpropion HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Diethylpropion hydrochloride is an amphetamine congener that is used as an anorexigenic agent.
Diethylpropion is used as an adjunct to caloric restriction in the short-term treatment (a few weeks) of exogenous obesity. The anorexigenic effect of sympathomimetic compounds used in the treatment of obesity is temporary, seldom lasting more than a few weeks and tolerance may occur. To help bring about and maintain loss of weight, the patient must be taught to curtail overeating and to consume a suitable diet.
As with other anorexigenic agents, prolonged administration of diethylpropion is not indicated.
Generic name: diethylpropion HCl
Pronunciation: (dye-ETH-il-PROE-pee-on)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Diethylpropion
Indications
The following indications are listed for Diethylpropion:
- Weight Loss Management For Obese Patient (body mass index 30 or greater)
Dosing
The recommended adult dosage of diethylpropion hydrochloride is 25 mg 3 times daily 1 hour before meals; an additional 25 mg may be given in midevening if necessary. The extended-release tablet containing 75 mg of the drug may be given once daily, in midmorning. When tolerance to the anorexigenic effect of diethylpropion develops, the recommended dosage should not be exceeded in an attempt to increase the effect, but instead the drug should be discontinued.
Diethylpropion hydrochloride is administered orally.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
Insulin requirements in patients with diabetes mellitus may be decreased in association with the use of diethylpropion and the concomitant dietary regimen and weight loss; therefore, diethylpropion should be administered with caution in patients with diabetes mellitus.
Like amphetamines, diethylpropion may decrease the hypotensive effect of guanethidine.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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No enhanced messaging available.
Safe use of diethylpropion during pregnancy has not been established. During pregnancy it is questionable whether potential benefits from anorexigenic agents outweigh potential risks and this condition should probably be considered a contraindication to their use, especially during the first trimester.
Since diethylpropion hydrochloride and/or its metabolites are excreted into milk in humans, the drug should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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