Nortriptyline (nortriptyline HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Nortriptyline is a dibenzocycloheptene-derivative tricyclic antidepressant drug that is the active metabolite of amitriptyline.
USES: This medication is used to treat depression. Nortriptyline belongs to a class of drugs known as tricyclic antidepressants. It works by helping to restore the balance of certain natural substances in the brain.
Generic name: nortriptyline HCl
Pronunciation: (nor-TRIP-ti-leen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Nortriptyline
Indications
The following indications are listed for Nortriptyline:
- Depression
Also known as: Depressed Mood, Depressive Disorder, Depressive Reaction, Depressive Syndrome, Mental Depression.
Dosing
Dosage of nortriptyline hydrochloride is expressed in terms of nortriptyline. There is a wide range of dosage requirements and dosage must be carefully individualized. Initial dosages should be low and may be gradually adjusted to the level that produces maximal therapeutic effect with minimal toxicity.
Patients should be monitored for possible worsening of depression, suicidality, or unusual changes in behavior, especially at the beginning of therapy or during periods of dosage adjustment. (See Cautions: Precautions and Contraindications, in the Tricyclic Antidepressants General Statement 28:16.04.28.)
Nortriptyline hydrochloride is administered orally. Although nortriptyline has been administered in up to 4 divided doses throughout the day, it is long-acting and the entire daily dose may be administered at one time.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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