Dyrenium (triamterene)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Triamterene is a potassium-sparing diuretic.
USES: Triamterene is a "water pill" (diuretic) that works in your kidneys to increase the amount of urine you make. This helps your body get rid of extra water. This medication is used to decrease swelling (edema) caused by conditions such as cancer, heart failure, liver disease, and kidney disease.
This effect can help your kidneys work better and lessen symptoms such as trouble breathing and swelling in your ankles, feet, hands, or belly.
Generic name: triamterene
Pronunciation: (trye-AM-ter-een)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Dyrenium
Indications
The following indications are listed for Dyrenium:
- Edema
- Peripheral Edema Due To Chronic Heart Failure
- Pulmonary Edema Due To Chronic Heart Failure
Also known as: Edematous Sodium Retaining Conditions, Peripheral Edema Due To Chf, Peripheral Edema Due To Congestive Heart Failure, Pulmonary Edema Due To Congestive Heart Failure.
Dosing
Dosage of triamterene should be individualized according to the patient's requirements and response. It has been theorized that abrupt withdrawal of triamterene may result in rebound kaliuresis; therefore, the drug should be withdrawn gradually. Experts state that diuretics should be administered at a dosage sufficient to achieve optimal volume status and relieve congestion without inducing an excessively rapid reduction in intravascular volume, which could result in hypotension, renal dysfunction, or both.
Triamterene is administered orally. Triamterene has been administered IV+, but the poor solubility of the drug and acidity of the solutions make administration by this route extremely difficult and a parenteral dosage form currently is not available in the US.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
There are no adequate and well-controlled studies using triamterene in pregnant women, and the drug should be used during pregnancy only when the potential benefits justify the possible risks (these include adverse effects reported in adults) to the fetus.
Since triamterene has been shown to distribute into milk in animals and may distribute into human milk, the drug should not be used in nursing women. If use of triamterene is deemed essential, nursing should be discontinued.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
Search health-plan coverage for this drug by ZIP code.
Choose the first character of a health plan name.
Last reviewed · Source: First Databank (FDB) drug data
On this page
Actions
Sign in to save favorites
Saving this drug requires a free Physicians Office Resource account.